Evidence map›Paper›PMID 41316108›Full record

ArticleBMC psychiatry2025

Lessons on catatonia with or without delirium on the consultation-liaison psychiatry service in a Lebanese tertiary care center: a retrospective chart review of 36 cases of catatonia.

Alfred Chabbouh, Roua Abbas, Majida Al Kurdi, Lea Daou, Yara El Frenn, Rawan Koleilat, Maha Makki, Hani Tamim, Rita Khoury

Abstract read
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Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Alfred Chabbouh *Department of Psychiatry, Faculty of Medicine, American University of Beirut, 11-0236 Riad El Solh, Beirut, 1107 2020, Lebanon.
Roua Abbas *Department of Psychiatry, Faculty of Medicine, American University of Beirut, 11-0236 Riad El Solh, Beirut, 1107 2020, Lebanon.
Majida Al KurdiDepartment of Psychiatry, Faculty of Medicine, American University of Beirut, 11-0236 Riad El Solh, Beirut, 1107 2020, Lebanon.
Lea DaouDepartment of Psychiatry, Faculty of Medicine, American University of Beirut, 11-0236 Riad El Solh, Beirut, 1107 2020, Lebanon.
Yara El FrennDepartment of Psychiatry, Faculty of Medicine, American University of Beirut, 11-0236 Riad El Solh, Beirut, 1107 2020, Lebanon.
Rawan KoleilatDepartment of Psychiatry, Faculty of Medicine, American University of Beirut, 11-0236 Riad El Solh, Beirut, 1107 2020, Lebanon.
Maha MakkiClinical Research Institute, American University of Beirut, Beirut, Lebanon.
Hani TamimClinical Research Institute, American University of Beirut, Beirut, Lebanon.
Rita KhouryDepartment of Psychiatry, Faculty of Medicine, American University of Beirut, 11-0236 Riad El Solh, Beirut, 1107 2020, Lebanon. rk224@aub.edu.lb.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCatatonia in the physically ill is an under-investigated topic and its diagnosis remains challenging, especially when it presents with comorbid delirium. In this study, we described the presentations and correlates of confirmed cases of catatonia stratified by the presence or absence of comorbid delirium.

methodsWe examined the electronic health records of 36 patients with catatonia due to general medical condition using the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria seen on the consultation-liaison Psychiatry service in a Lebanese tertiary care center. We collected variables pertaining to demographic and diagnostic information, past medical history, Bush-Francis Scale, catatonia signs and symptoms, as well as diagnostic investigations when performed.

resultsThe mean age was 55.5 ± 19.1 years, and 52% were males. 27% of patients had a history of a non-psychiatric brain disease, and 36% had a history of psychiatric diagnoses. 22% had a history of thrombotic disorders. 50% of the participants had comorbid delirium with catatonia (DeliCat syndrome). Patients with DeliCat were significantly older (64.3 ± 14.8 vs. 46.6 ± 19.1) and had significantly higher rates of history of thrombotic disorders (38% vs. 5%) compared to catatonia-only patients. Other paraclinical investigations did not differ statistically between the groups.

conclusionsThe study highlights the overlap between delirium and catatonia. Based on existing literature, we propose a model that conceptualizes catatonia and delirium as maladaptive sickness responses related to neuroinflammation and the defense cascade. This model has the potential to explain the shared pathophysiology of the two syndromes, offering a framework for future investigations.

Indexed as

CatatoniaDeliriumAdultAgedComorbidityFemaleHumansLebanonMaleMiddle AgedReferral and ConsultationRetrospective StudiesTertiary Care CentersCatatoniaConsultation-LiaisonDeliriumEvolutionaryMedicalPsychiatry

Identifiers

PMID41316108
PMCPMC12751219

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