Evidence map›Paper›PMID 41316045›Full record

ArticleBMC geriatrics2025

The concept of multidimensional frailty in geriatric oncology: a systematic scoping review.

Yinning Guo, Yimeng Chen, Shulin Song, Ziyan Wang, Yue Chen, Zhongmin Fu, Xinyi Xu, Qin Xu, Lingyu Ding

Abstract readScoping Review
In one paragraph

Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yinning GuoSchool of Nursing, Nanjing Medical University, 101Longmian Avenue, Jiangning District, Nanjing, 211166, China.
Yimeng ChenSchool of Nursing, Nanjing Medical University, 101Longmian Avenue, Jiangning District, Nanjing, 211166, China.
Shulin SongSchool of Nursing, Nanjing Medical University, 101Longmian Avenue, Jiangning District, Nanjing, 211166, China.
Ziyan WangSchool of Nursing, Nanjing Medical University, 101Longmian Avenue, Jiangning District, Nanjing, 211166, China.
Yue ChenSchool of Nursing, Nanjing Medical University, 101Longmian Avenue, Jiangning District, Nanjing, 211166, China.
Zhongmin FuSchool of Nursing, Nanjing Medical University, 101Longmian Avenue, Jiangning District, Nanjing, 211166, China.
Xinyi XuSchool of Nursing, Nanjing Medical University, 101Longmian Avenue, Jiangning District, Nanjing, 211166, China.
Qin XuSchool of Nursing, Nanjing Medical University, 101Longmian Avenue, Jiangning District, Nanjing, 211166, China. qinxu@njmu.edu.cn.
Lingyu DingDepartment of Colorectal Surgery, the First Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road, Gulou District, Nanjing, 210000, China. lingyuding@163.com.

Funding

4th Priority Discipline Development Program of Jiangsu Higher Education Institutions(Jiangsu Education Department 2023 No.11Jiangsu Province Postgraduate Scientific Research Innovation Program KYCX25_2198National Natural Science Foundation of China No: 72404140National Natural Science Foundation of China No: 82073407
6 · The paper itself

Abstract

backgroundOne of the major challenges in geriatric oncology is to estimate the risk-benefit balance of any therapeutic proposal for each patient and frailty is one of the key components of Comprehensive Geriatric Assessment (CGA)and can also be assessed using stand-alone screening tools that predicts functional decline, treatment-related complications and mortality. This study aimed to provide an overview of the existing literature on the concept of multidimensional frailty in older adults with cancer, to clarify the dimensions included in multidimensional frailty, and the components of frailty under each dimension.

methodsWe followed the PRISMA guidelines and Arksey and O’Malley’s framework for scoping reviews, and the research question was developed according to the participants-concept-context (PCC) framework. We searched for literature related to multidimensional frailty concepts in the field of geriatric oncology published in multiple databases from database inception to December 2024 and used a data extraction form to extract and analyze the data

resultsThe final scoping review included 25 studies, which were pooled to find that multidimensional frailty was a syndrome that centred on physical dimension, but also encompassing psychological, social, cognitive and oral dimensions. To better characterise multidimensional frailty, we summarised the components specific to frailty under each dimension.

conclusionOur study provides a systematic overview of the concepts, dimensions, and components of multidimensional frailty in the field of geriatric oncology, which may contribute to the construction of an effective frailty assessment tool with a minimum number of dimensions to predict serious adverse events for older adults with cancer, as well as being important for the prevention and management of frailty, and for oncological rehabilitation. CLINICAL TRIAL NUMBER: not applicable.

Indexed as

Frail ElderlyFrailtyGeriatric AssessmentGeriatricsMedical OncologyNeoplasmsAgedHumansConceptMultidimensional frailtyOlder adults with cancerScoping review

Identifiers

PMID41316045
PMCPMC12661781

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.