SynthesisBMC medical imaging2025
Comparison of photon-counting CT angiography with energy-integrating CT angiography in coronary artery stenosis: a systematic review and meta-analysis.
Synthesis in BMC medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Photon-counting computed tomography in coronary artery bypass grafting planning and follow-up: a narrative review of a high-resolution adjunct to invasive angiography.Journal of thoracic disease · 2026Review
- Influence of Cardiac Motion on Stent Lumen Visibility in Photon-Counting CT Employing a Pulsatile Heart Model.Diagnostics (Basel, Switzerland) · 2026Article
- Comparison of Non-Contrast Coronary MRA Image Quality at 5T and 3T Based on the SCCT Segmental Model: A Technical Feasibility Study in Healthy Volunteers.Journal of clinical medicine · 2026Article
- Photon-Counting CT Angiography Enables Superior Preoperative Perforator Depiction for Fibular Transplant Surgery Requiring Less Contrast Agent Compared to Energy-Integrating CT.Diagnostics (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo perform CT-angiography of coronary arteries, energy-integrating detector computed tomography (EID-CT) is widely used but it has several limitations, especially in overestimation of size of calcium plaques. Photon-counting detector computed tomography (PCD-CT) promises better image quality and lower radiation. This study compares the efficacy, radiation dose, and image quality of EID-CT and PCD-CT for coronary artery disease (CAD) diagnosis. MATERIALS AND
methodsA systematic review and meta-analysis were conducted per PRISMA guidelines. Four databases were searched for studies directly comparing EID-CT and PCD-CT. Data on coronary artery calcium scores (CACS), radiation dose index (mGy), dose-length product (DLP), and image quality were extracted. Risk of bias was assessed using the QUADAS-C tool.
resultsTwelve studies with 213 patients were included. PCD-CT showed a significant reduction in dose index (standardized mean difference (SMD) = -0.62, 95% CI: -0.89 to -0.35, p < 0.001) and DLP (SMD = -0.66, 95% CI: -0.98 to -0.35, p < 0.001) compared to EID-CT. Quantitative data for image quality and artifacts was limited, but qualitative assessments indicated PCD-CT's superior performance in reducing beam-hardening artifacts and providing clearer images of calcified plaques. No significant difference was found in CACS between the modalities (intraclass correlation coefficient (ICC) = 0.992, 95% CI: 0.981 to 1.000) based on individual patient data. PCD-CT results in reduced percentage and grade of stenosis compared to EID-CT in the available data.
conclusionPCD-CT has been suggested to offer better image quality and lower radiation dose compared to EID-CT, especially in visualizing calcified plaques. There is some evidence of less overestimation with PCD-CT, which should be confirmed by further studies. CLINICAL TRIAL NUMBER: Not applicable.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.