Trial reportBMC anesthesiology2025
Is there a difference in the postoperative quality of recovery and analgesia between erector spinae and serratus anterior plane blocks following modified radical mastectomy: a randomized controlled study.
Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04296188 (Comparison of Erector Spina Plane Block and Serratus Anterior Plane Block in Patients Undergoing Mastectomy), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Comparison of Erector Spina Plane Block and Serratus Anterior Plane Block in Patients Undergoing Mastectomy
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe postoperative recovery quality of patients may be associated with the efficacy of perioperative analgesia management. The effects of erector spinae plane block (ESPB) and serratus anterior plane block (SAPB) on the quality of recovery following breast cancer surgery have not been clearly established. The objective of the present study is to assess the quality of recovery and analgesic efficiency of ESPB and SAPB as postoperative analgesia methods in modified radical mastectomy surgeries.
methodsA total of 68 female patients undergoing modified radical mastectomy were randomly separated into two groups. The main outcome of this randomized, double-blind prospective study was the 40-item global quality of recovery (QoR-40) questionnaire score, collected at 24 and 48 h postoperatively. Other measures of interest included postoperative numerical rating scale (NRS), cumulative opioid consumption, time to first analgesic request, demographic data, hemodynamic variables and postoperative complications such as nausea, vomiting and dizziness.
resultsIn the postoperative period after 24 h, the global QoR-40 scores were found as 185.5 (range:150–199) in the ESPB group and 186 (range:158–198) in the SAPB group (p = 0.304). The median time to first analgesic request was 645 min (range:30–740) in the ESPB group and 640 min (range:30–700) in the SAPB group, without any statistical variation between the groups (p = 0.216). Cumulative opioid consumption did not significantly differ between the two groups (p = 0.785). Likewise, no significant difference was detected between the ESPB and SAPB groups in mean arterial pressure, heart rate, SpO₂ levels or complication rates.
conclusionPreoperative administration of ESPB and SAPB in breast cancer surgery improved the quality of recovery and effectively reduced analgesic requirement. Future studies should investigate how local anesthetic type and volume affect postoperative recovery and analgesia.
trial registrationClinicalTrials.gov ID: NCT04296188 on 03/03/2020.
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