Evidence map›Paper›PMID 41315849›Full record

SynthesisScientific reports2025

The bacterial spectrum of spinal infections based on blood culture, tissue culture, and molecular methods: a systematic review and meta-analysis.

Rui Zhang, Mengdie Wang, Xinyu Liu, Feifei Yang, Xinyuan Xu, Liye Zi, Zhi Liang, Xiaorong Liu, Hongbing Gao, Xuesong Chen and 1 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rui ZhangFaculty of Life Science and Technology & The affiliated Anning First People's Hospital, Kunming University of Science and Technology, Kunming, 650302, China.
Mengdie WangFaculty of Life Science and Technology & The affiliated Anning First People's Hospital, Kunming University of Science and Technology, Kunming, 650302, China.
Xinyu LiuFaculty of Life Science and Technology & The affiliated Anning First People's Hospital, Kunming University of Science and Technology, Kunming, 650302, China.
Feifei YangFaculty of Life Science and Technology & The affiliated Anning First People's Hospital, Kunming University of Science and Technology, Kunming, 650302, China.
Xinyuan XuDepartment of Pain Medicine, The Affiliated Anning First People's Hospital of Kunming University of Science and Technology, Kunming, 650302, Yunnan, China.
Liye ZiDepartment of Pain Medicine, The Affiliated Anning First People's Hospital of Kunming University of Science and Technology, Kunming, 650302, Yunnan, China.
Zhi LiangDepartment of Pain Medicine, The Affiliated Anning First People's Hospital of Kunming University of Science and Technology, Kunming, 650302, Yunnan, China.
Xiaorong LiuDepartment of Pain Medicine, The Affiliated Anning First People's Hospital of Kunming University of Science and Technology, Kunming, 650302, Yunnan, China.
Hongbing GaoDepartment of Pain Medicine, The Affiliated Anning First People's Hospital of Kunming University of Science and Technology, Kunming, 650302, Yunnan, China.
Xuesong ChenDepartment of Pain Medicine, The Affiliated Anning First People's Hospital of Kunming University of Science and Technology, Kunming, 650302, Yunnan, China. jinhou0420@163.com.
Guozhong ZhouDepartment of Pain Medicine, The Affiliated Anning First People's Hospital of Kunming University of Science and Technology, Kunming, 650302, Yunnan, China. 20220247@kust.edu.cn.

Funding

Yunnan Fundamental Research Projects CB23059C065A
6 · The paper itself

Abstract

Spinal infections (SI) are on the rise due to an aging population and the prevalence of more invasive procedures. This study aims to systematically review the microbiological spectrum of SI to enhance diagnostic accuracy and inform effective antibiotic treatment strategies. The last search was conducted on May 9th, 2024, from databases including EMBASE, PubMed, and Web of Science. The outcome variable is infection rate, and the detection method used should be blood culture, tissue culture, or molecular biology method. Two researchers independently extracted research data and evaluated its quality using the JBI Critical Appraisal Tools. Out of 14,639 identified records, 156 studies (encompassing 13,539 patients) were included. Staphylococcus aureus was identified as the most prevalent pathogen, with pooled infection rates of 17.6% (95%CI: 12.8-22.9%; I

Indexed as

BacteriaBacterial InfectionsSpinal DiseasesBlood CultureHigh-Throughput Nucleotide SequencingHumansMycobacterium tuberculosisStaphylococcus aureusBacterial infection spectrumBlood cultureMeta-analysisMolecular biology methodSpinal infectionsTissue culture

Identifiers

PMID41315849
PMCPMC12753679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.