Evidence map›Paper›PMID 41315843›Full record

ArticleScientific reports2025

Cost-effectiveness of chest radiography using artificial intelligence for lung cancer screening in South Korea.

KyungYi Kim, Jung Hyun Kim, Jaeyong Shin, Man S Kim, Sang-Hoon Park, Jung Hyun Chang, Chang-Hoon Han, Si Nae Oh

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

KyungYi KimDepartment of Biohealth Industry, Graduate School of Transdisciplinary Health Sciences, Yonsei University, Seoul, Republic of Korea.ORCID 0000-0002-7856-3255
Jung Hyun KimDivision of Tourism and Wellness, Hankuk University of Foreign Studies (HUFS), Yongin, Republic of Korea.ORCID 0000-0003-4248-3760
Jaeyong ShinDepartment of Preventive Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-2955-6382
Man S KimTranslational-Transdisciplinary Research Center, Clinical Research Institute, Kyung Hee University, Seoul, Republic of Korea.ORCID 0000-0002-1507-9829
Sang-Hoon ParkDepartment of Orthopedic Surgery, National Health Insurance Service Ilsan Hospital, Goyang, Republic of Korea.ORCID 0000-0002-9085-6667
Jung Hyun ChangDepartment of Otorhinolaryngology, National Health Insurance Service Ilsan Hospital, Goyang, Republic of Korea.ORCID 0000-0002-9771-6528
Chang-Hoon HanDepartment of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Republic of Korea.ORCID 0000-0002-4664-8924
Si Nae OhYonsei Institute for Digital Health, Yonsei University, 50-1, Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea. ohsinae@yuhs.ac.ORCID 0000-0003-2452-6069

Funding

Korea Health Industry Development Institute (KHIDI) HI22C1580
6 · The paper itself

Abstract

Artificial intelligence (AI) shows promise in improving the accuracy and efficiency of lung cancer screening, but its economic value remains uncertain. We developed a decision-analytic model combining a decision tree and Markov model to evaluate five screening strategies in South Korea: no screening, chest X-ray (CXR), AI-assisted CXR, low-dose computed tomography (LDCT), and AI-assisted LDCT. We simulated hypothetical cohorts of 10,000 individuals, stratified by age group and smoking status to reflect the Korean population distribution, and projected their lifetime costs and quality-adjusted life years (QALYs). Analyses applied a 4.5% discount rate and a willingness-to-pay (WTP) threshold of $32,409.9 per QALY. AI-assisted CXR produced incremental cost-effectiveness ratio (ICER) of $8679-$10,030 per QALY, demonstrating cost-effectiveness across all age groups. CXR alone was less favorable, and LDCT-based strategies exceeded the willingness-to-pay (WTP) threshold. These findings suggest AI-assisted CXR offers a scalable, economically viable strategy for lung cancer screening, supporting its integration into national programs.

Indexed as

Artificial IntelligenceCost-Benefit AnalysisEarly Detection of CancerLung NeoplasmsRadiography, ThoracicAdultAgedFemaleHumansMaleMarkov ChainsMass ScreeningMiddle AgedQuality-Adjusted Life YearsRepublic of KoreaTomography, X-Ray Computed

Identifiers

PMID41315843
PMCPMC12753820

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.