Evidence map›Paper›PMID 41315815›Full record

ArticleNature methods2026

DeepCor: denoising fMRI data with contrastive autoencoders.

Yu Zhu, Aidas Aglinskas, Stefano Anzellotti

Abstract read
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In one paragraph

Article in Nature methods, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yu Zhu *Department of Psychology and Neuroscience, Boston College, Boston, MA, USA. polly.yuzhu@gmail.com.ORCID http://orcid.org/0009-0000-3617-0261
Aidas Aglinskas *Department of Psychology and Neuroscience, Boston College, Boston, MA, USA.ORCID http://orcid.org/0000-0001-5207-3277
Stefano AnzellottiDepartment of Psychology and Neuroscience, Boston College, Boston, MA, USA. stefano.anzellotti@bc.edu.ORCID http://orcid.org/0000-0002-8964-6988

Funding

Boston College (BC) Startup Grant to Stefano AnzellottiNational Science Foundation (NSF) 1943862
6 · The paper itself

Abstract

Functional magnetic resonance imaging (fMRI) allows noninvasive measurement of neural activity with high spatial resolution. However, fMRI data are affected by noise. Here we introduce and evaluate a denoising method (DeepCor) that utilizes deep generative models to disentangle and remove noise. The method is applicable to data from single participants. DeepCor outperforms other state-of-the-art denoising approaches on a variety of simulated datasets. In real fMRI data, DeepCor enhances BOLD signal responses to face stimuli, outperforming CompCor by 215%.

Indexed as

BrainBrain MappingImage Processing, Computer-AssistedMagnetic Resonance ImagingAlgorithmsAutoencoderComputer SimulationHumansSignal-To-Noise Ratio

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.