Evidence map›Paper›PMID 41315785›Full record

ArticleNature materials2026

Self-assembled cell-scale containers made from DNA origami membranes.

Christoph Karfusehr, Markus Eder, Hao Yuan Yang, Brice Beinsteiner, Marion Jasnin, Friedrich C Simmel

Abstract read
In one paragraph

Article in Nature materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Hierarchical Assembly of Multilayer Core-Shell DNA Origami Crystals.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. From toroids to helical tubules: Kirigami-inspired programmable assembly of two-periodic curved crystals from DNA origami.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christoph KarfusehrDepartment of Bioscience, TUM School of Natural Sciences, Technical University Munich, Garching, Germany.ORCID 0000-0003-1634-2657
Markus EderDepartment of Bioscience, TUM School of Natural Sciences, Technical University Munich, Garching, Germany.
Hao Yuan YangDepartment of Bioscience, TUM School of Natural Sciences, Technical University Munich, Garching, Germany.ORCID 0009-0008-6579-1858
Brice BeinsteinerHelmholtz Pioneer Campus, Helmholtz Munich, Neuherberg, Germany.ORCID 0000-0002-4873-0550
Marion JasninHelmholtz Pioneer Campus, Helmholtz Munich, Neuherberg, Germany.ORCID 0000-0003-1726-4566
Friedrich C SimmelDepartment of Bioscience, TUM School of Natural Sciences, Technical University Munich, Garching, Germany. simmel@tum.de.ORCID 0000-0003-3829-3446

Funding

Bundesministerium für Bildung und Forschung (Federal Ministry of Education and Research) TUM Innovation Network RISE
6 · The paper itself

Abstract

Biological compartmentalization creates and controls localized environments to ensure that chemical processes are efficient, thus enabling life's complexity and functionality. Biological systems use crystalline protein cages for nanoscale compartments, whereas larger, dynamic structures, such as vesicles and cell membranes, are formed from lipid bilayers. Although membrane-based approaches have prevailed in bottom-up synthetic biology, DNA and protein nanotechnology has focused on designing rigid cage assemblies. Here we report on the self-assembly of radially symmetric DNA origami subunits that are inspired by the structure and interactions of lipids. The formed DNA origami monolayer membranes can be readily programmed to form vesicles or hollow tubes with diameters ranging from 100 nm to over 1 μm. These DNA origami membranes represent an approach for compartmentalization that opens possibilities in bottom-up biology and cell-scale soft robotics.

Indexed as

DNAMembranes, ArtificialNanostructuresLipid BilayersNanotechnologyNucleic Acid ConformationDNALipid BilayersMembranes, Artificial

Identifiers

PMID41315785
PMCPMC12960257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.