Evidence map›Paper›PMID 41315640›Full record

ArticleScientific reports2025

In vitro phytochemical and biological evaluation of hydroethanolic extract of Anchomanes difformis In Togo.

Tchilabalo Bouyo, Komi Komi Koukoura, Sandrine Tènè Salifou, Passimna Pissang, Efui Holaly Gbekley, Yao Hoekou, Blaise Etienne M'boumba, Jules Koffi Kpatagnon, Bawimodom Bidjada, Kodjovi Sossou and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Tchilabalo BouyoLaboratory of Biomedical, Food and Environmental Health Sciences - Biomedical Sciences and Bioactive Substances Research Unit (LaSBASE - UR-2SB), Ecole Supérieure des Techniques Biologiques et Alimentaires (ESTBA), University of Lomé, Lomé, Togo. saint3esprit@gmail.com.ORCID 0000-0003-2954-1970
Komi Komi KoukouraLaboratory of Biomedical, Food and Environmental Health Sciences - Biomedical Sciences and Bioactive Substances Research Unit (LaSBASE - UR-2SB), Ecole Supérieure des Techniques Biologiques et Alimentaires (ESTBA), University of Lomé, Lomé, Togo.
Sandrine Tènè SalifouLaboratory of Biomedical, Food and Environmental Health Sciences - Biomedical Sciences and Bioactive Substances Research Unit (LaSBASE - UR-2SB), Ecole Supérieure des Techniques Biologiques et Alimentaires (ESTBA), University of Lomé, Lomé, Togo.
Passimna PissangLaboratory of Biomedical, Food and Environmental Health Sciences - Biomedical Sciences and Bioactive Substances Research Unit (LaSBASE - UR-2SB), Ecole Supérieure des Techniques Biologiques et Alimentaires (ESTBA), University of Lomé, Lomé, Togo.
Efui Holaly GbekleyLaboratory of Biomedical, Food and Environmental Health Sciences - Biomedical Sciences and Bioactive Substances Research Unit (LaSBASE - UR-2SB), Ecole Supérieure des Techniques Biologiques et Alimentaires (ESTBA), University of Lomé, Lomé, Togo.
Yao HoekouLaboratory of Biomedical, Food and Environmental Health Sciences - Biomedical Sciences and Bioactive Substances Research Unit (LaSBASE - UR-2SB), Ecole Supérieure des Techniques Biologiques et Alimentaires (ESTBA), University of Lomé, Lomé, Togo.
Blaise Etienne M'boumbaLaboratory for Research on Agroresources and Environmental Health (LARASE), Higher School of Agronomy, University of Lomé, Lomé, Togo.
Jules Koffi KpatagnonLaboratory of Biomedical, Food and Environmental Health Sciences - Biomedical Sciences and Bioactive Substances Research Unit (LaSBASE - UR-2SB), Ecole Supérieure des Techniques Biologiques et Alimentaires (ESTBA), University of Lomé, Lomé, Togo.
Bawimodom BidjadaBacteriology Laboratory, National Institute Hygiene of Lomé, Lomé, Togo.
Kodjovi SossouLaboratory of Biomedical, Food and Environmental Health Sciences - Biomedical Sciences and Bioactive Substances Research Unit (LaSBASE - UR-2SB), Ecole Supérieure des Techniques Biologiques et Alimentaires (ESTBA), University of Lomé, Lomé, Togo.
Abdoul Kader OuedraogoLaboratory of Biomedical, Food and Environmental Health Sciences - Biomedical Sciences and Bioactive Substances Research Unit (LaSBASE - UR-2SB), Ecole Supérieure des Techniques Biologiques et Alimentaires (ESTBA), University of Lomé, Lomé, Togo.
Komla TchallaLaboratory of Biomedical, Food and Environmental Health Sciences - Biomedical Sciences and Bioactive Substances Research Unit (LaSBASE - UR-2SB), Ecole Supérieure des Techniques Biologiques et Alimentaires (ESTBA), University of Lomé, Lomé, Togo.
Samadou TchakondoLaboratory of Biomedical, Food and Environmental Health Sciences - Biomedical Sciences and Bioactive Substances Research Unit (LaSBASE - UR-2SB), Ecole Supérieure des Techniques Biologiques et Alimentaires (ESTBA), University of Lomé, Lomé, Togo.
Isidore Kodzovi Anani GbenonsiLaboratory of Biomedical, Food and Environmental Health Sciences - Biomedical Sciences and Bioactive Substances Research Unit (LaSBASE - UR-2SB), Ecole Supérieure des Techniques Biologiques et Alimentaires (ESTBA), University of Lomé, Lomé, Togo.
Richard Kouyassa DessougmbaFaculty of Health Sciences, University of Lomé, Lomé, Togo.
Tchadjobo TchacondoLaboratory of Biomedical, Food and Environmental Health Sciences - Biomedical Sciences and Bioactive Substances Research Unit (LaSBASE - UR-2SB), Ecole Supérieure des Techniques Biologiques et Alimentaires (ESTBA), University of Lomé, Lomé, Togo.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing proliferation of strains that are multidrug-resistant to conventional antibiotics has created a pressing need to explore alternative bioactive compounds. This study aimed to evaluate the antimicrobial activity of different organs of Anchomanes difformis, a medicinal plant widely used in the traditional pharmacopoeia of West Africa, against Escherichia coli, Staphylococcus aureus, Streptococcus pneumoniae, and Candida albicans. Total hydroethanolic extracts from the leaves, bulbs, and rhizomes were obtained by maceration. The phytochemical composition of the extracts was assessed qualitatively using standard staining techniques to identify major secondary metabolite groups. Total flavonoid content was quantified spectrophotometrically. Antioxidant activity was evaluated using two complementary methods: the phosphomolybdate reduction assay and the FRAP (Ferric Reducing Antioxidant Power) test. In vitro antimicrobial activity was assessed by solid diffusion methods (well and disk diffusion assays). The highest hydroethanolic extraction yield was recorded for the leaf bark extract of A. difformis (9.47%). Phytochemical screening revealed the presence of alkaloids, coumarins, and reducing sugars. The bulb extract exhibited the highest total flavonoid content (33.78 µg R Eq /mg DE). The leaf extract demonstrated strong in vitro antioxidant potential, with 37.79 AA Eq /g DE and 270.50 µmol FeSO

Indexed as

Anti-Infective AgentsPhytochemicalsPlant ExtractsAnti-Bacterial AgentsAntioxidantsCandida albicansEscherichia coliEthanolFlavonoidsMicrobial Sensitivity TestsPlant LeavesPlants, MedicinalStaphylococcus aureusTogoAnti-Bacterial AgentsAnti-Infective AgentsAntioxidantsEthanolFlavonoidsPhytochemicalsPlant ExtractsActivityAnchomanes difformisAntimicrobialAntioxidantPhytochemistry

Identifiers

PMID41315640
PMCPMC12753731

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.