Evidence map›Paper›PMID 41315467›Full record

ArticleScientific reports2025

Diagnostic accuracy of Transmitted-light plethysmography for the assessment of pulpal circulation in traumatized young permanent incisors.

Satoko Kakino, Hiroaki Ohki, Kaori Kohi, Yuko Matsumura, Tsutomu Iwamoto

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Satoko KakinoDepartment of Pediatric Dentistry/Dentistry for Persons with Special Needs, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan. satokopd.pedo@tmd.ac.jp.
Hiroaki OhkiDepartment of Pediatric Dentistry/Dentistry for Persons with Special Needs, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan.
Kaori KohiDepartment of Pediatric Dentistry/Dentistry for Persons with Special Needs, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan.
Yuko MatsumuraDepartment of Pediatric Dentistry/Dentistry for Persons with Special Needs, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan.
Tsutomu IwamotoDepartment of Pediatric Dentistry/Dentistry for Persons with Special Needs, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan.

Funding

a Grant-in-Aid for Scientific Research (C) from the Ministry of Education, Culture, Sports, Science, and Technology of Japan 23K09195
6 · The paper itself

Abstract

Transmitted light plethysmography (TLP) is a noninvasive, objective optical method used to assess dental pulp circulation and evaluate pulp vitality. This study aimed to develop a quantitative diagnostic approach for TLP and assess its accuracy through cross-correlation analysis of plethysmographic signals obtained from both the tooth and the finger. A total of 131 maxillary incisors from 97 pediatric patients (aged 6-17 years) were categorized into three groups: nontraumatized teeth, traumatized vital teeth, and traumatized nonvital teeth. Standard diagnostic procedures, including assessments for discoloration, percussion sensitivity, periapical translucency, and electric pulp testing (EPT), were performed alongside TLP evaluation, 3 to 18 months following dental trauma. Tooth plethysmograms were acquired using a 525 nm light-emitting diode directed through the examined teeth, while simultaneous finger plethysmograms were recorded as reference signals. Cross-correlation coefficients (R-values; 0 < R < 1) were calculated between the tooth and finger signals for each tooth, and diagnostic cutoff thresholds were determined using receiver operating characteristic (ROC) curve analysis based on the maximum Youden index. Statistically significant differences in R-values were observed among the three groups. The optimal diagnostic cutoff was identified as 0.40 (95% confidence interval: 0.38-0.45), at which TLP demonstrated a sensitivity of 0.94 and a specificity of 0.88, outperforming EPT. Logistic regression analysis incorporating all pulp testing methods revealed a significant association with pulp vitality status. Furthermore, the area under the ROC curve (AUC) for TLP combined with standard tests was significantly greater than that of any individual model. These results indicate that TLP offers improved diagnostic precision for identifying nonvital pulp and may serve as a valuable adjunct to conventional pulp vitality assessments.

Indexed as

Dental PulpIncisorPlethysmographyTooth InjuriesAdolescentChildDental Pulp TestFemaleHumansMaleROC CurveCross-correlation analysisDiagnostic accuracyPulpal blood flowPulp vitalityTransmitted-light plethysmography (TLP)

Identifiers

PMID41315467
PMCPMC12663260

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