Evidence map›Paper›PMID 41315148›Full record

ArticleBiological trace element research2026

Hexavalent Chromium and Hexavalent Uranium Induce Mitochondrial Damage and Transcriptomic Alterations in Chinese Soft-Shelled Turtle Embryo Fibroblasts.

Zhihui Xiao, Pengfei Liao, Chunping Mao, Wenying Shen, Chaonan Zhang, Xiaodong Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in Biological trace element research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhihui XiaoCollege of Life and Environmental Science, Shaoxing University, Shaoxing, 312000, China.
Pengfei LiaoCollege of Biological and Environmental Science, Zhejiang Wanli University, Ningbo, 315100, China.
Chunping MaoCollege of Life and Environmental Science, Shaoxing University, Shaoxing, 312000, China.
Wenying ShenCollege of Life and Environmental Science, Shaoxing University, Shaoxing, 312000, China.
Chaonan ZhangCollege of Life and Environmental Science, Shaoxing University, Shaoxing, 312000, China.
Xiaodong ZhangCollege of Life and Environmental Science, Shaoxing University, Shaoxing, 312000, China. 13676885816@163.com.

Funding

National Natural Science Foundation of China 42307533
6 · The paper itself

Abstract

Hexavalent chromium [Cr(VI)] and hexavalent uranium [U(VI)] are common heavy metal pollutants in aquatic environments, which are harmful to aquatic organisms. As a keystone species representing reptiles in freshwater ecosystems, Chinese soft-shelled turtles serve as sentinel species in environmental monitoring. However, the toxic effects of these heavy metal pollutants on this species have not been fully elucidated. This study investigated the toxic effects, and underlying mechanisms of Cr(VI) and U(VI) on Chinese soft-shelled turtle embryo fibroblasts (CSSTEF). Cell toxicity assay results showed that exposure to both Cr(VI) and U(VI) reduced the viability of CSSTEF cells, with half maximal inhibitory concentrations (IC

Indexed as

ChromiumFibroblastsMitochondriaTranscriptomeTurtlesUraniumAnimalsCell SurvivalEmbryo, NonmammalianWater Pollutants, ChemicalChromiumchromium hexavalent ionUraniumWater Pollutants, ChemicalCellular toxicityChinese soft-shelled turtle embryo fibroblastsCr(VI)IC50U(VI)

Identifiers

PMID41315148

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.