Evidence map›Paper›PMID 41315125›Full record

ArticleJournal of medical systems2025

Clinical Accuracy and Safety Concerns Following GPT-5 Public Demonstration in Cancer Care.

Ivan Capobianco, Andrea Della Penna, André L Mihaljevic, Michael Bitzer, Carsten Eickhoff, Derna Stifini

Abstract readLetter
In one paragraph

Article in Journal of medical systems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ivan CapobiancoDepartment of General, Visceral and Transplant Surgery, University Hospital Tuebingen, Tuebingen, Germany. ivan.capobianco@med.uni-tuebingen.de.
Andrea Della PennaDepartment of General, Visceral and Transplant Surgery, University Hospital Tuebingen, Tuebingen, Germany.
André L MihaljevicDepartment of General, Visceral and Transplant Surgery, University Hospital Tuebingen, Tuebingen, Germany.
Michael BitzerDepartment of Internal Medicine I, University Hospital Tuebingen, Tuebingen, Germany.
Carsten EickhoffCenter for Digital Health, University Hospital Tuebingen, Tuebingen, Germany.
Derna StifiniDepartment of General, Visceral and Transplant Surgery, University Hospital Tuebingen, Tuebingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

OpenAI's GPT-5 demonstration showed a patient uploading pathology reports to guide treatment decisions, though privacy implications were not addressed. We evaluated GPT-5 against 100 gastrointestinal oncology cases with tumor-board validation and found identical 85% concordance to GPT-4o, contradicting superiority claims. We recommend mandatory accuracy disclosures and regulatory oversight for AI health demonstrations to protect patient safety and privacy.

Indexed as

Gastrointestinal NeoplasmsPatient SafetyHumans

Identifiers

PMID41315125
PMCPMC12662883

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.