Evidence map›Paper›PMID 41315053›Full record

ArticleInfluenza and other respiratory viruses2025

The Epidemiology, Phylogeny, and Strain Antigenicity of an Influenza A/H3N2 Virus Outbreak Among Vaccinated US Navy Midshipmen.

Simon D Pollett, Emily Hone, Stephanie A Richard, Kat Schmidt, Mark P Simons, Michele Wayman, Jennifer Rothenberg, Vivian Hogan, Robert J O'Connell, Timothy H Burgess and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Influenza and other respiratory viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Simon D PollettInfectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0002-4450-7028
Emily HoneInfectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Stephanie A RichardInfectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0002-0530-384X
Kat SchmidtInfectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Mark P SimonsInfectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Michele WaymanInfectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Jennifer RothenbergInfectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Vivian HoganInfectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Robert J O'ConnellInfectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Timothy H BurgessInfectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Daniel EwingAgile Vaccines and Therapeutics Department, Naval Medical Research Command, Silver Spring, Maryland, USA.
Appavu K SundaramAgile Vaccines and Therapeutics Department, Naval Medical Research Command, Silver Spring, Maryland, USA.
Anthony C FriesUnited States Air Force School of Aerospace Medicine (USAFSAM), Wright-Patterson Air Force Base, Dayton, Ohio, USA.
Drake H TilleyNaval Health Clinic Annapolis, Annapolis, Maryland, USA.
Rhonda E ColomboInfectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.

Funding

Armed Forces Health Surveillance Division (AFHSD), Global Emerging Infections Surveillance (GEIS) Branch P0058_24_NMDefense Health Agency Armed Forces Health Surveillance Division Global Emerging Infections Surveillance (GEIS) Program P0064_23_HSDefense Health Program HU00012120103
6 · The paper itself

Abstract

We performed epidemiological, genetic, and antigenic characterization of an influenza A/H3N2 outbreak in a congregate setting of young adults with high vaccination rates. We noted substantial duty-days lost, rapid spread, and vaccine antigenic divergence. The risk of influenza in healthy vaccinated adults underscores the need to develop universal influenza vaccines.

Indexed as

Disease OutbreaksInfluenza A Virus, H3N2 SubtypeInfluenza, HumanInfluenza VaccinesMilitary PersonnelAdultAntigens, ViralHumansMalePhylogenyUnited StatesVaccinationYoung AdultAntigens, ViralInfluenza Vaccinesepidemiologyinfluenza A/H3N2outbreakphylogenyUS navyvaccinated

Identifiers

PMID41315053
PMCPMC12981523

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.