Evidence map›Paper›PMID 41314838›Full record

ArticleBMJ open2025

Disparities in post-traumatic neurodegeneration among adults of African American or Black racial identity: a scoping review protocol.

Maria Lee, Tadeusz Hayduk Wroblewski, Mommina Ashaque, Marie-Claire Roberts, Robert W Turner, Tim B Bigdeli, Ernest J Barthélemy

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria LeeCollege of Medicine, SUNY Downstate Health Sciences University, New York, New York, USA.ORCID http://orcid.org/0009-0002-0214-2785
Tadeusz Hayduk WroblewskiCollege of Medicine, SUNY Downstate Health Sciences University, New York, New York, USA.ORCID http://orcid.org/0000-0002-8082-1997
Mommina AshaqueGlobal Neurosurgery Laboratory, Division of Neurosurgery, Department of Surgery, SUNY Downstate Health Sciences University, New York, New York, USA.
Marie-Claire RobertsGlobal Neurosurgery Laboratory, Division of Neurosurgery, Department of Surgery, SUNY Downstate Health Sciences University, New York, New York, USA.
Robert W TurnerDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.ORCID http://orcid.org/0000-0003-4229-7087
Tim B BigdeliDepartment of Psychiatry and the Behavioral Sciences, SUNY Downstate Health Sciences University, New York, New York, USA.
Ernest J BarthélemyGlobal Neurosurgery Laboratory, Division of Neurosurgery, Department of Surgery, SUNY Downstate Health Sciences University, New York, New York, USA ernest.barthelemy@downstate.edu.

Funding

Clinical Research Scholars Training (CREST) ProgramR25MD017950 · NIMHD · SUNY DOWNSTATE MEDICAL CENTER · PI Carla Boutin-Foster, Marlene Camacho · 2022 to 2026
$2.6M
NIMHD NIH HHS R25 MD017950
6 · The paper itself

Abstract

introductionThis scoping review will evaluate and synthesise what is known about the impact of structural and social determinants of health on neurodegeneration among adults of African American or Black (AAB) racial identity with a history of traumatic brain injury (TBI). The primary objective is to examine how structural factors, such as healthcare access, influence disparities in neurodegeneration following TBI. Given higher rates of TBI and worse outcomes among Black individuals compared with White individuals, this review seeks to fill the gap in research concerning underrepresentation of AAB populations. METHODS AND ANALYSIS: Guided by the Joanna Briggs Institute Evidence framework, this review will systematically search PubMed (MEDLINE), Embase and Cochrane CENTRAL Library (Wiley) for relevant studies. Eligible studies will involve adult human participants diagnosed with neurodegenerative conditions, including dementia and cognitive impairment, and with a history of TBI. Studies must include participants of AAB and non-Hispanic White (NHW) racial identity to facilitate comparisons. The review will focus on identifying potential factors contributing to disparities in neurodegeneration. Data synthesis will include narrative summaries, comparative tables and visualisations to highlight racial disparities in neurodegeneration risk and AAB representation in TBI research. This approach is its structured framework will evaluate the depth of racial inclusion across studies, allowing for a more nuanced understanding of how structural and social determinants shape outcomes. ETHICS AND DISSEMINATION: As this review involves only previously published literature, institutional review board approval will not be required. The findings will be disseminated through peer-reviewed publications, conference presentations and lay summaries.

Indexed as

Black or African AmericanBrain Injuries, TraumaticHealthcare DisparitiesHealth Status DisparitiesNeurodegenerative DiseasesAdultHumansResearch DesignScoping Reviews as TopicSocial Determinants of HealthWhiteBrain InjuriesCognitive dysfunctionDementiaHealth EquityReview

Identifiers

PMID41314838
PMCPMC12666191

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.