Evidence map›Paper›PMID 41314821›Full record

ArticleBMJ open2025

From knowledge to action: protocol for a mixed-methods evaluation of First Nations-led knowledge mobilisation on prenatal opioid exposure.

Priscilla Medeiros, Agnes Mazzucco, Lauren Wilkinson, Marcia Altiman, Jennifer Glover, Ashley Stone, Bailley Taylor, Astrid Guttmann, Serene Kerpan

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Priscilla MedeirosEdwin S.H. Leong Centre for Healthy Children, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0003-1050-6067
Agnes MazzuccoEdwin S.H. Leong Centre for Healthy Children, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0009-0002-2681-0186
Lauren WilkinsonEdwin S.H. Leong Centre for Healthy Children, University of Toronto, Toronto, Ontario, Canada.
Marcia AltimanCommunity Member, Walpole Island First Nation, Walpole Island, Ontario, Canada.
Jennifer GloverCommunity Member, Walpole Island First Nation, Walpole Island, Ontario, Canada.
Ashley StoneCommunity Member, Aamjiwnaang First Nation, Sarnia, Ontario, Canada.
Bailley TaylorCommunity Member, Curve Lake First Nation, Curve Lake, Ontario, Canada.
Astrid GuttmannEdwin S.H. Leong Centre for Healthy Children, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0001-8177-2253
Serene KerpanICES, Toronto, Ontario, Canada serene.kerpan@viu.ca.ORCID http://orcid.org/0009-0007-9753-8358

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFirst Nations communities in Canada are disproportionately impacted by prenatal opioid exposure (POE) and neonatal abstinence syndrome (NAS). In response, we developed a research partnership with 13 First Nations communities in Ontario. Phase I of the research project, initiated in 2018, included the development of mixed-methods reports on the impact of POE for each community. This protocol outlines the evaluation of phase II, during which nine communities individually co-designed and implemented community-specific knowledge mobilisation (KMb) plans informed by findings from phase I. The evaluation aims to assess advisory working group engagement, KMb implementation and perceived community-level impacts. METHODS AND ANALYSIS: This mixed-methods evaluation integrates survey and qualitative data to assess First Nations-led KMb products and activities. The Public and Patient Engagement Evaluation Tool, a validated survey instrument, will be administered to advisory group members and analysed descriptively. Focus groups and interviews will be conducted to explore advisory working group members' experiences and analysed using phenomenological methods. Qualitative findings will be mapped to the Engage with Impact framework to assess outcomes across engagement domains. ETHICS AND DISSEMINATION: Ethics approval has been granted by Vancouver Island University. All community contacts and advisory working group members will provide informed consent prior to data collection. Phase II activities are governed by formal community agreements. In alignment with First Nations Principles of OCAP (Ownership, Control, Access and Possession), First Nations community partners retain ownership of their KMb products and are actively involved in the design, implementation and dissemination of the project evaluation. Results will be shared through peer-reviewed publications, community reports and knowledge-sharing events.

Indexed as

Analgesics, OpioidIndigenous CanadiansNeonatal Abstinence SyndromeOpioid-Related DisordersPrenatal Exposure Delayed EffectsFemaleFocus GroupsHumansOntarioPregnancyQualitative ResearchResearch DesignSurveys and QuestionnairesAnalgesics, OpioidCommunity-Based Participatory ResearchKnowledgeMethodsQUALITATIVE RESEARCH

Identifiers

PMID41314821
PMCPMC12666137

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.