Evidence map›Paper›PMID 41314784›Full record

SynthesisBritish journal of sports medicine2026

Cam morphology and the risk of developing radiographic hip osteoarthritis within 8 years: an individual participant data meta-analysis of 23 886 hips from the world COACH consortium.

Jinchi Tang, Fleur Boel, Michiel Ma van Buuren, Noortje S Riedstra, Myrthe A van den Berg, Harbeer Ahedi, Nigel K Arden, Sita M A Bierma-Zeinstra, Cindy G Boer, Flavia Cicutini and 18 more

Abstract readMeta-Analysis
In one paragraph

Synthesis in British journal of sports medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Is cam morphology a cause of osteoarthritis?Nature reviews. Rheumatology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Jinchi TangDepartment of Orthopaedics and Sports Medicine, Erasmus MC University Medical Center, Rotterdam, Netherlands.ORCID http://orcid.org/0000-0002-1028-5922
Fleur BoelDepartment of Orthopaedics and Sports Medicine, Erasmus MC University Medical Center, Rotterdam, Netherlands.ORCID http://orcid.org/0000-0002-0421-9478
Michiel Ma van BuurenDepartment of Orthopaedics and Sports Medicine, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Noortje S RiedstraDepartment of Orthopaedics and Sports Medicine, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Myrthe A van den BergDepartment of Orthopaedics and Sports Medicine, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Harbeer AhediUniversity of Tasmania, Hobart, Tasmania, Australia.
Nigel K ArdenNuffield Department of Orthopaedics, University of Oxford, Oxford, UK.
Sita M A Bierma-ZeinstraDepartment of Orthopaedics and Sports Medicine, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Cindy G BoerDepartment of Internal Medicine, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Flavia CicutiniDepartment of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Timothy CootesUniversity of Manchester, Manchester, UK.
Kay M CrossleyLa Trobe University, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0001-5892-129X
David T FelsonBoston University School of Medicine, Boston, Massachusetts, USA.
Willem-Paul GielisDepartment of Orthopedics, University Medical Center Utrecht, Utrecht, Netherlands.
Joshua J HeereyLa Trobe Sport and Exercise Medicine Research Centre, School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0001-8691-1830
Graeme JonesUniversity of Tasmania, Hobart, Tasmania, Australia.
Stefan KluzekUniversity of Nottingham, Nottingham, UK.
Nancy E LaneDepartment of Medicine, University of California at Davis, Sacramento, California, USA.
Claudia LindnerUniversity of Manchester, Manchester, UK.
John A LynchDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA.
Joyce van MeursDepartment of Orthopaedics and Sports Medicine, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Andrea Britt MoslerLa Trobe Sport and Exercise Medicine Research Centre, La Trobe University - Bundoora Campus, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0001-7353-2583
Amanda E NelsonThurston Arthritis Research Center, Chapel Hill, North Carolina, USA.
Michael NevittDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA.
Edwin H G OeiDepartment of Radiology & Nuclear Medicine, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Jos RunhaarDepartment of General Practice, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Harrie WeinansDepartment of Biomechanical Engineering, Delft University of Technology, Delft, Netherlands.
Rintje AgricolaDepartment of Orthopaedics and Sports Medicine, Erasmus MC University Medical Center, Rotterdam, Netherlands r.agricola@erasmusmc.nl.ORCID http://orcid.org/0000-0002-0645-093X

Funding

Study of Osteoporotic FracturesR01AG005407 · NIA · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI CUMMINGS, STEVEN RON, YAFFE, KRISTINE · 1986 to 2016
$23.2M
Multicenter Osteoarthritis Study (MOST) Second RenewalU01AG019069 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NEVITT, MICHAEL C · 2001 to 2020
$21.7M
Multicenter Osteoarthritis Study (MOST) Second Renewal: Iowa Clinical CenterU01AG018832 · NIA · UNIVERSITY OF IOWA · PI SEGAL, NEIL A, TORNER, JAMES C · 2001 to 2020
$14.1M
Multicenter Osteoarthritis Study (MOST) Second Renewal - Boston UniversityU01AG018820 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FELSON, DAVID TOBIN · 2001 to 2019
$13.6M
Multicenter Osteoarthritis Study (MOST) Second Renewal - UAB Clinical CenterU01AG018947 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E · 2001 to 2020
$13.2M
Study of Osteoporotic FracturesR01AG005394 · NIA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI ENSRUD, KRISTINE · 1986 to 2015
$6.1M
UNC Core Center for Clinical ResearchP30AR072580 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LEIGH Fleming CALLAHAN, Amanda E Nelson · 2019 to 2026
$6.1M
Project 3P60AR049465 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JORDAN, JOANNE M. · 2003 to 2008
$6.0M
NIAMS Multidisciplinary Clinical Research CenterP60AR064166 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SCHWARTZ, TODD A · 2013 to 2017
$5.8M
STUDY OF OSTEOPOROTIC FRACTURES: VERTEBRAL FRACTURESR01AR035583 · NIAMS · KAISER FOUNDATION RESEARCH INSTITUTE · PI HILLIER, TERESA A · 1986 to 2005
$3.2M
Study of Osteoporotic Fractures (SOF)R01AG027574 · NIA · KAISER FOUNDATION RESEARCH INSTITUTE · PI HILLIER, TERESA A · 2006 to 2015
$2.6M
Study of Osteoporotic Fractures (SOF)-Pittsburgh ClinicR01AG027576 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CAULEY, JANE ANN · 2006 to 2015
$2.4M
NCCDPHP CDC HHS U01 DP003206NCCDPHP CDC HHS U01 DP006266NIAMS NIH HHS P30 AR072580NIAMS NIH HHS P60 AR030701NIAMS NIH HHS P60 AR049465NIAMS NIH HHS P60 AR064166NIAMS NIH HHS R01 AR035582NIAMS NIH HHS R01 AR035583NIAMS NIH HHS R01 AR035584NIA NIH HHS R01 AG005394NIA NIH HHS R01 AG005407NIA NIH HHS R01 AG027574NIA NIH HHS R01 AG027576NIA NIH HHS U01 AG018820NIA NIH HHS U01 AG018832NIA NIH HHS U01 AG018947NIA NIH HHS U01 AG019069Wellcome Trust 223267
6 · The paper itself

Abstract

objectiveTo assess the relationship between cam morphology and the development of radiographic hip osteoarthritis (RHOA), overall and in subgroups based on age, biological sex and body mass index (BMI).

methodsHips with no RHOA at baseline and with available follow-up during 4-8 years were selected from the Worldwide Collaboration on Osteoarthritis PrediCtion for the Hip (World COACH) consortium. Alpha angles were uniformly measured on anteroposterior radiographs, with a threshold of 60

resultsA total of 23 886 hips were included (mean age: 62.2±8.4 years; 70.6% female; BMI: 27.4±4.5; mean time to follow-up: 6.1±3.0 years). Cam morphology was associated with RHOA (OR: 1.87, 95% CI 1.36 to 2.59), as was a greater alpha angle (OR 1.02, 95% CI 1.01 to 1.03 for every degree increase). The overall relative risk of developing RHOA in hips with cam morphology was 1.62 (95%CI 1.26 to 2.07), greatest for those aged 51-60 years (2.15, 95% CI 1.55 to 2.98) and higher in males (2.50, 95% CI 1.67 to 3.73), compared with females (1.75,95% CI 1.24 to 2.48).

conclusionHips with cam morphology have higher odds of developing RHOA within 4-8 years compared with hips without cam morphology. The relative risk was highest in subgroups of participants aged 51-60 years and in males, making cam morphology a potential target for primary or secondary prevention of RHOA.

Indexed as

Femoracetabular ImpingementHip JointOsteoarthritis, HipAgedAge FactorsBody Mass IndexFemaleHumansMaleMiddle AgedRadiographyRisk FactorsSex FactorsCohort StudiesHipOsteoarthritis

Identifiers

PMID41314784
PMCPMC7618585

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.