Evidence map›Paper›PMID 41314078›Full record

ArticleDevelopmental cognitive neuroscience2026

Precision functional neuroimaging reveals individually specific auditory responses in infants.

Julia Moser, Alyssa K Labonte, Thomas J Madison, Lana Hantzsch, Han H N Pham, Kimberly B Weldon, M Catalina Camacho, Rebecca F Schwarzlose, Sanju Koirala, Jacob T Lundquist and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Developmental cognitive neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Precision functional imaging in infants using multi-echo fMRI at 7T.bioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Julia MoserMasonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA. Electronic address: moser297@umn.edu.
Alyssa K LabonteDepartment of Psychiatry, Washington University in St. Louis, St. Louis, MO, USA; Neurosciences Graduate Program, Washington University in St. Louis, St. Louis, MO, USA.
Thomas J MadisonMasonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA.
Lana HantzschMasonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA; Institute of Child Development, University of Minnesota, Minneapolis, MN, USA.
Han H N PhamMasonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA.
Kimberly B WeldonMasonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA.
M Catalina CamachoDepartment of Psychiatry, Washington University in St. Louis, St. Louis, MO, USA.
Rebecca F SchwarzloseDepartment of Psychiatry, Washington University in St. Louis, St. Louis, MO, USA.
Sanju KoiralaMasonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA; Institute of Child Development, University of Minnesota, Minneapolis, MN, USA.
Jacob T LundquistMasonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA.
Sooyeon SungMasonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA; Graduate School of Education, Kyung Hee University, Seoul, Republic of Korea.
Cristian Morales CarrascoMasonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA; Biomedical Engineering, Universidad de Santiago, Santiago, Chile.
Robert J M HermosilloMasonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA; Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, USA.
Steven M NelsonMasonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
Jed T ElisonMasonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA; Institute of Child Development, University of Minnesota, Minneapolis, MN, USA; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
Damien A FairMasonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA; Institute of Child Development, University of Minnesota, Minneapolis, MN, USA; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
Chad M SylvesterDepartment of Psychiatry, Washington University in St. Louis, St. Louis, MO, USA; Department of Radiology, Washington University in St. Louis, St. Louis, MO, USA; Taylor Family Institute for Innovative Psychiatric Research, Washington University in St. Louis, St. Louis, MO, USA.

Funding

Individualized Mechanisms of Neural Plasticity and Response to Interventions in NeonatesR01MH134966 · NIMH · WASHINGTON UNIVERSITY · PI Chad Michael Sylvester · 2024 to 2026
$4.2M
Neonatal Brain Activity and Risk for Anxiety Disorders in Early ChildhoodR01MH122389 · NIMH · WASHINGTON UNIVERSITY · PI Chad Michael Sylvester · 2020 to 2026
$3.9M
Neural mechanisms of sensory over-responsivity in children with and without ASDR00HD109454 · NICHD · WASHINGTON UNIVERSITY · PI Rebecca Schwarzlose · 2024 to 2026
$747k
Neural mechanisms of sensory over-responsivity in children with and without ASDK99HD109454 · NICHD · WASHINGTON UNIVERSITY · PI SCHWARZLOSE, REBECCA · 2022 to 2023
$263k
NICHD NIH HHS K99 HD109454NICHD NIH HHS R00 HD109454NIMH NIH HHS R01 MH122389NIMH NIH HHS R01 MH134966
6 · The paper itself

Abstract

Adaptively responding to salient stimuli in the environment is a fundamental feature of cognitive development in early life, which is enabled by the developing brain. Understanding individual variability in how the brain supports this fundamental process is essential for uncovering neurodevelopmental trajectories and potential neurodevelopmental risks. In the present study, we used a precision functional imaging approach to probe activation in response to salient auditory stimuli and its relation to brain functional networks in individual infants. A minimum of 60 min of fMRI BOLD data with an auditory oddball paradigm were collected in ten infants with a mean postmenstrual age of 48 weeks. Results demonstrate the feasibility of conducting a precision functional imaging study to investigate individual specific responses to salient stimuli in infants. While responses to the auditory oddball were consistent across individuals in auditory processing areas, responses across the rest of the brain differed across individuals in their magnitude and time to peak. Individual specific response patterns appeared to be relatively stable and differed from other participant's response patterns, despite fluctuations across runs. Commonalities and differences between individuals demonstrated in this sample contribute to our understanding of how the developing brain instantiates processing of salient stimuli. In this context, individual specific response patterns could be a promising target for biomarkers of normative brain and cognitive development.

Indexed as

Auditory PerceptionBrainFunctional NeuroimagingAcoustic StimulationBrain MappingFemaleHumansIndividualityInfantMagnetic Resonance ImagingMaleAuditory processingIndividual brain developmentInfant brain imagingPrecision functional imagingTask fMRI

Identifiers

PMID41314078
PMCPMC12702346

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.