Evidence map›Paper›PMID 41313730›Full record

SynthesisNursing open2025

Quality of Life in Chronic Heart Failure With Obstructive Sleep Apnea: A Systematic Review.

Francesco Limonti, Giovanni Cangelosi, Diaratou Dabre, Gianluca Marino, Arcangelo Correra, Sara Morales Palomares, Nicola Ramacciati, Francesco Gravante

Abstract readSystematic Review
In one paragraph

Synthesis in Nursing open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Francesco LimontiDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
Giovanni CangelosiExperimental Medicine and 'Stefania Scuri' Public Health Department, University of Camerino, Camerino, Italy.
Diaratou DabreDepartment of Translational Medicine, University of Naples 'L. Vanvitelli', Napoli, Italy.
Gianluca MarinoDepartment of Translational Medicine, University of Naples 'L. Vanvitelli', Napoli, Italy.
Arcangelo CorreraDepartment of Strategic Services, Local Health Authority of Caserta, Caserta, Italy.
Sara Morales PalomaresDepartment of Pharmacy, Health and Nutritional Sciences (DFSSN), University of Calabria, Rende, Italy.ORCID https://orcid.org/0009-0003-3884-4823
Nicola RamacciatiDepartment of Pharmacy, Health and Nutritional Sciences (DFSSN), University of Calabria, Rende, Italy.ORCID https://orcid.org/0000-0002-1176-8133
Francesco GravanteDepartment of Critical Care, San Giuseppe Moscati, Local Health Authority of Caserta, Aversa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo describe the quality of life in patients with chronic heart failure and coexisting obstructive sleep apnoea, and to examine the effect of common sleep-disordered breathing treatments on quality of life, functional capacity and cardiac outcomes.

designSystematic review.

methodsThis systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and was registered in PROSPERO (CRD42025634352). DATA SOURCES: A comprehensive search was conducted in PubMed, CINAHL, Scopus and Web of Science up to March 2024. Study quality was assessed using the Joanna Briggs Institute Critical Appraisal Checklists.

resultsFourteen studies were included, involving 2048 patients with chronic heart failure and sleep-disordered breathing, including obstructive and central sleep apnea. Sleep-disordered breathing was associated with reduced quality of life, physical capacity and cardiac function. Continuous positive airway pressure improved respiratory events, sleep quality, left ventricular function and exercise performance. Adaptive servo-ventilation reduced central respiratory events but was associated with increased mortality in patients with reduced left ventricular function. Nocturnal oxygen therapy improved some respiratory parameters but did not affect quality of life. Structured exercise programs showed benefits for functional status and quality of life.

conclusionObstructive sleep apnea negatively affects the quality of life in people with chronic heart failure. Continuous positive airway pressure is beneficial in selected patients, while adaptive servo-ventilation should be used cautiously. Personalised approaches are needed. IMPLICATIONS FOR THE PROFESSION AND/OR PATIENT CARE: Systematic screening and individualised care plans, including nurse-led management, are key to improving quality of life and outcomes in this population. IMPACT: What problem did the study address? The insufficient understanding of how obstructive sleep apnea influences quality of life in chronic heart failure. What were the main findings? Some interventions improved quality of life, while others showed safety concerns. Where and on whom will the research have an impact? The findings guide clinical care for adults with chronic heart failure and coexisting sleep-disordered breathing. REPORTING

methodWe have adhered to the EQUATOR guidelines according to PRISMA. PATIENT OR PUBLIC CONTRIBUTION: No patient or public contribution.

Indexed as

Heart FailureQuality of LifeSleep Apnea, ObstructiveChronic DiseaseHumanschronic heart failureobstructive sleep apneaquality of lifesleep apneasystematic review

Identifiers

PMID41313730
PMCPMC12662253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.