Trial reportRevista da Escola de Enfermagem da U S P2025
Evaluation of the effectiveness of solutions for clearing neonatal central venous catheters: randomized study.
Trial report in Revista da Escola de Enfermagem da U S P, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Neonatal epicutaneo-cava catheter-related thrombosis: a comprehensive overview.Thrombosis journal · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the effectiveness of saline, heparin, and vitamin C solutions in unclogging neonatal central venous catheters occluded by clots.
methodA randomized, double-blind, in vitro experimental study conducted in August 2022 with 90 neonatal central venous catheters occluded with blood that remained in a water bath for 8 hours. The solutions tested were: saline, heparin (50 mg/ml), and vitamin C (25 mg/ml), using a negative pressure technique. The variables of number of attempts and time to unclogging were evaluated in relation to the mean and standard deviation. For variables with abnormal distribution, the Kruskal-Wallis test was used.
resultsThere was no statistical significance in relation to the time and number of attempts to unclog the three solutions (p > 0.05), and the maximum time to unclog the catheters was 120 minutes.
conclusionThe three substances showed similar results. Thus, saline solution is recommended because it is considered safe, with fewer side effects when used in newborns.
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Registered trials
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