Evidence map›Paper›PMID 41313210›Full record

ArticlemBio2026

A single-domain response regulator activates exopolysaccharide biosynthesis by interaction with the initiating phosphoglycosyl transferase.

Johannes Schwabe, Julia Monjaras-Feria, Timo Glatter, Patrick Blumenkamp, Oliver Rupp, Alexander Goesmann, Miguel A Valvano, Lotte Søgaard-Andersen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Johannes SchwabeDepartment of Ecophysiology, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany.
Julia Monjaras-FeriaInfection Biology Group, Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom.
Timo GlatterCore Facility for Mass Spectrometry and Proteomics, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany.
Patrick BlumenkampSystems Biology and Bioinformatics, Justus Liebig University Gießen, Gießen, Germany.
Oliver RuppSystems Biology and Bioinformatics, Justus Liebig University Gießen, Gießen, Germany.
Alexander GoesmannSystems Biology and Bioinformatics, Justus Liebig University Gießen, Gießen, Germany.
Miguel A ValvanoInfection Biology Group, Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom.ORCID 0000-0001-8229-3641
Lotte Søgaard-AndersenDepartment of Ecophysiology, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany.ORCID 0000-0002-0674-0013

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exported polysaccharides play crucial functions in bacteria. Polysaccharide biosynthesis in the ubiquitous Wzx/Wzy- and ABC-transporter-dependent pathways starts with the transfer of a sugar-1-phosphate from a nucleotide-sugar donor to undecaprenyl phosphate, a reaction catalyzed by a phosphoglycosyl transferase (PGT). Both reaction substrates are limited and shared among multiple glycoconjugate pathways, raising the question of how bacteria regulate these pathways. In

Indexed as

Bacterial ProteinsGene Expression Regulation, BacterialMyxococcus xanthusPolysaccharides, BacterialPhosphorylationProtein BindingBacterial ProteinsPolysaccharides, BacterialmonoPGTphosphoglycosyl transferasepolysaccharide biosynthesisproximity labelingresponse regulatorWzxWzy

Identifiers

PMID41313210
PMCPMC12802240

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.