ArticleMicrobiology spectrum2026
Combining an antibiotic stewardship program with a 15-pathogen viral panel to reduce inappropriate antibiotic prescribing.
Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Current practice and timing of rapid point-of-care testing for acute respiratory tract infections in outpatient care: a retrospective cohort study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Charting new territory: outpatient stewardship in immunocompromised patients (first of a two-part series).Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Acute upper respiratory tract infections (ARI) frequently result in unnecessary antibiotic prescribing in outpatient settings, contributing to antibiotic resistance and avoidable adverse outcomes. While antimicrobial stewardship programs (ASPs) have shown promise, their implementation in urgent care settings remains limited. The impact of point-of-care (POC) respiratory viral panels on antibiotic prescribing is also uncertain. This study evaluates the effect of the BIOFIRE SPOTFIRE Respiratory Panel, a 15-pathogen panel, with integrated ASP interventions on antibiotic prescribing in a high-volume urgent care setting in the Southeast United States. This was a prospective cohort study of adults with ARI who presented to an urgent care in Louisiana from June to August 2024. A randomly selected, seasonally matched, historic usual care group served as a control group. We compared the impact of BIOFIRE SPOTFIRE Respiratory Panel testing and ASP on antibiotic prescribing. A total of 296 patients were prospectively enrolled, with 600 randomly selected historical controls. The intervention group had a significantly lower antibiotic prescribing rate (24.3% vs 38.2%; adjusted odds ratio (aOR) 0.50, 95% confidence interval (CI) 0.36-0.68) and inappropriate antibiotic use rate (15.9% vs 30.8%; aOR 0.39, 95% CI 0.28-0.57) compared to controls. Steroid prescribing also decreased (17.9% vs 29.0%; aOR 0.55, 95% CI 0.39-0.78). Implementation of a POC multirespiratory pathogen molecular test combined with an ASP intervention significantly reduced antibiotic and steroid prescribing in a high-volume urgent care setting. IMPORTANCE: Acute upper respiratory tract infections are common and often result in unnecessary antibiotic prescribing. We found a significant reduction in inappropriate antibiotic use after implementing an antibiotic stewardship program with a point-of-care respiratory viral panel in an urgent care setting.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.