ArticleMicrobiology spectrum2026
Diagnostic accuracy of the BD MAX MDR-TB assay on sputum and tongue swabs for
Anura David, Lyndel Singh, Manuel Pedro da Silva, Keneilwe Peloakgosi-Shikwambani, Zanele Nsingwane, Violet Molepo, Wendy Stevens, Lesley Erica Scott
Abstract read
In one paragraphArticle in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
8 authors.
Anura DavidWits Diagnostics Innovation Hub, Health Sciences Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0003-1590-198X Lyndel SinghWits Diagnostics Innovation Hub, Health Sciences Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Manuel Pedro da SilvaNational Priority Programmes, National Health Laboratory Services, Johannesburg, South Africa.
Keneilwe Peloakgosi-ShikwambaniWits Diagnostics Innovation Hub, Health Sciences Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Zanele NsingwaneWits Diagnostics Innovation Hub, Health Sciences Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Violet MolepoWits Diagnostics Innovation Hub, Health Sciences Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Wendy StevensWits Diagnostics Innovation Hub, Health Sciences Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Lesley Erica ScottWits Diagnostics Innovation Hub, Health Sciences Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Funding
Bill and Melinda Gates Foundation OPP1171455
6 · The paper itselfAbstract
Despite the availability of molecular diagnostics, only 48% of newly diagnosed tuberculosis (TB) cases were confirmed using nucleic acid amplification tests in 2023. The MAX Multi Drug Resistant Tuberculosis (MAX MDR-TB) assay detects IMPORTANCE: This study evaluates the accuracy of the BD MAXTM MDR-TB assay in detecting
Indexed as
Molecular Diagnostic TechniquesMycobacterium tuberculosisSputumTongueTuberculosis, Multidrug-ResistantAdultAntitubercular AgentsDrug Resistance, Multiple, BacterialFemaleHumansIsoniazidMaleMiddle AgedRifampinSensitivity and SpecificitySouth AfricaAntitubercular AgentsIsoniazidRifampinBD MAX DR-TBisoniazidMycobacterium tuberculosisNAATrifampicin
Identifiers
PMID41313021
PMCPMC12772227
What OpenQuestion holds
Textmetadata
LicenceCC BY
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