Evidence map›Paper›PMID 41312938›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2025

Comparison of Dose-Volume Histograms of Three Whole Breast Radiotherapy Regimes: Conventional, Normal Hypofractionation and FAST-FORWARD Hypofractionation.

Amir Hossein Nabizadeh-Javan, Pezhman Porouhan, Zeinab Jalambadani, Seyed Alireza Javadinia, Reza Chaman, Gaurav Dhawan, Gunjan Sharma, Vikas Dhawan, Ruhollah Ghahramani-Asl

Abstract readComparative Study
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Article in Asian Pacific journal of cancer prevention : APJCP, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Amir Hossein Nabizadeh-JavanStudent Research Committee, Sabzevar University of Medical Sciences, Sabzevar, Iran.
Pezhman PorouhanDepartment of Radiation Oncology, Vasee Hospital, Sabzevar University of Medical Sciences, Sabzevar, Iran.
Zeinab JalambadaniStudent Research Committee, Sabzevar University of Medical Sciences, Sabzevar, Iran.
Seyed Alireza JavadiniaNon-Communicable Diseases Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran.ORCID 0000-0003-2467-837X
Reza ChamanNon-Communicable Diseases Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran.
Gaurav DhawanSri Guru Ram Das (SGRD), University of Health Sciences, Amritsar, India and Independent Consultant, Hartford, CT, United States.
Gunjan SharmaMedical Physicist, Government Medical College, Amritsar, India.
Vikas DhawanUrologist, Commanding Officer, Field Hospital, Jammu and Kashmir, India.
Ruhollah Ghahramani-AslNon-Communicable Diseases Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran.ORCID 0000-0002-8807-6741

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to compare dose-volume histograms of three whole breast radiotherapy regimes there are: conventional radiotherapy (CRT), normal hypofractionation (NHRT) and FAST-FORWARD hypofractionation radiotherapy (FFRT).

methodsThis retrospective single-center study was conducted in the radiotherapy department of Vasei Hospital in Sabzevar, Iran in 2024. The therapeutic dose for the chest/whole breast and regional lymph nodes was administered using CRT (50Gy/2Gy/25Fx), NHRT (42.56Gy/2.66Gy/16Fx), and FFRT (26Gy/5.2Gy/5Fx) regimens.

resultsThe results of this study showed no statistically significant difference in the average scores of PTV V95%, PTV V107-110%, conformity index, and homogeneity index among the CRT, NHRT and FFRT treatment regimens. However, the average scores of PTV Dmean, lung Vmean, and heart Vmean were significantly higher for CRT and NHRT relative to FFRT group.

conclusionThe CRT is not superior to the NHRT and FFRT regimes, and in some cases, especially NHRT, they can be used interchangeably in the unique conditions and crowded government medical centers to provide more treatment services to patients and lower financial burden to the healthcare system.

Indexed as

Breast NeoplasmsRadiation Dose HypofractionationRadiotherapy Planning, Computer-AssistedAdultDose Fractionation, RadiationFemaleFollow-Up StudiesHumansIranMiddle AgedOrgans at RiskPrognosisRadiotherapy DosageRetrospective Studiesbreast cancerconventional radiotherapyFAST-FORWARD hypofractionationHypofractionationwhole breast radiotherapy

Identifiers

PMID41312938
PMCPMC12936126

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