ArticleJournal of cosmetic dermatology2025
Increased Prevalence of Insulin Resistance and Metabolic Syndrome in Men With Early-Onset Androgenetic Alopecia: A Case-Control Study.
Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Androgenetic alopecia in polycystic ovary syndrome: a cutaneous marker of systemic metabo-inflammatory and endocrine dysfunction.Endocrine connections · 2026Review
- Increased Prevalence of Insulin Resistance and Metabolic Syndrome in Men With Early-Onset Androgenetic Alopecia: A Case-Control Study.Journal of cosmetic dermatology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThis study aimed to investigate the relationship between early-onset androgenetic alopecia (AGA) and the prevalence of insulin resistance (IR) and metabolic syndrome (MetS) in young adult males.
methodsA total of 200 males aged 18 to 35 years were enrolled in this case-control study, including 100 patients with early-onset AGA and 100 age- and body mass index-matched controls. Clinical staging was performed using the Hamilton-Norwood classification, and all participants underwent standardized physical and biochemical evaluation.
resultsThe prevalence of insulin resistance (HOMA-IR ≥ 2.7) was significantly higher in the AGA group compared to the control group (18% vs. 4%, p = 0.003). Similarly, MetS was more common among AGA patients (21% vs. 9%, p = 0.011). Fasting insulin levels, triglyceride concentrations, and HOMA-IR scores were all significantly elevated in the AGA group, while HDL-C levels were comparable between groups. Waist circumference was also significantly greater in the AGA group (p = 0.026). When stratified by AGA severity, the frequency of IR progressively increased with increasing Hamilton-Norwood stages. No significant differences were observed in fasting glucose or blood pressure categories. Although individual MetS components were similar, cumulative clustering of risk factors appeared to be associated with a significantly higher MetS frequency among patients with AGA.
conclusionEarly-onset AGA in men may serve as a visible clinical indicator of underlying metabolic disturbances, particularly IR. Routine metabolic screening may be advisable in young men presenting with advanced AGA stage.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.