ArticleCanadian liver journal2025
Prevalence of neurodevelopmental disorders in children with chronic hepatitis C in British Columbia.
Article in Canadian liver journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chronic hepatitis C (HCV) in children is primarily acquired through vertical transmission from an HCV-infected mother. The primary risk factor for chronic HCV in mothers is intravenous drug use, which, in pregnancy, is associated with increased risk of neurodevelopmental disorders in children. We explored the prevalence of neurodevelopmental disorders among children with chronic HCV in British Columbia. Methods: Retrospective chart review was conducted for children actively followed for HCV at our centre between December 2020 and April 2024. Data were collected on demographic and clinical information including diagnoses of neurodevelopmental disorders and other learning difficulties. Results: We identified 29 children under 18 years of age (13 male, 16 female); 28 had HCV due to vertical transmission and 1 for unknown reasons, potentially due to the patient's own substance use. Forty-eight percent (n = 14) of patients had attention deficit hyperactivity disorder (ADHD). Among these, 43% (n = 6) had fetal alcohol spectrum disorder, 21% ( Conclusions: In our study population of children with chronic HCV, a majority had at least one documented neurodevelopmental disorder, representing a previously undescribed issue among pediatric patients with chronic HCV. We suggest practitioners who care for children with chronic HCV may have a role in proactively identifying patients with neurodevelopmental difficulties and linking them with appropriate resources.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.