ArticleCerebral circulation - cognition and behavior2025
Late-onset dementia with leukoencephalopathy and a
Article in Cerebral circulation - cognition and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Isoform Remodeling and Promoter Switching Identify Altered Transcriptional Regulation in Alzheimer's Disease Frontal Cortex.Research square · 2026Article
- Late Cognitive or Mood Alterations With 'Status Cribrosum' and Diffuse White Matter Lesions: A New Cerebral Small Vessel Disease Phenotype Associated With Rare COL4A1 Variants Located Within Exon 23.European journal of neurology · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Cerebral small vessel disease can manifest as vascular dementia, typically associated with vascular risk factors or cerebral amyloid angiopathy, and more rarely associated with hereditary conditions. We present a case of late-onset dementia, associated with a likely pathogenic Case Presentation: A 74-year-old woman presented with cognitive decline and behavioral changes, without personal history of cerebral infarcts or intracerebral hemorrhage. Brain MRI revealed an extensive leukoencephalopathy affecting periventricular and deep white matter, including subcortical white matter in the anterior temporal lobes and the orbitofrontal regions. Genetic analysis identified a heterozygous glycine substitution within the triple-helical domain of Conclusion:
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Registered trials
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