Evidence map›Paper›PMID 41312451›Full record

SynthesisVascular health and risk management2025

Artificial Intelligence in Cerebrovascular Disease Management: A Comprehensive Review of Risk Prediction, Diagnosis, Therapeutic Optimization, and Clinical Translation.

Hengsheng Zhang, Wenhui Ma, Xingshun Zhou, Zinlin Zhao, Runjun Zhang, Hong Bai, Cong Huang, Yujun Wang

Abstract readSystematic Review
In one paragraph

Synthesis in Vascular health and risk management, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hengsheng ZhangDepartment of Radiology, No. 926 Hospital, Joint Logistics Support Force of PLA, Kaiyuan, Yunnan, 661699, People's Republic of China.
Wenhui MaDepartment of Radiology, No. 926 Hospital, Joint Logistics Support Force of PLA, Kaiyuan, Yunnan, 661699, People's Republic of China.
Xingshun ZhouDepartment of Radiology, No. 926 Hospital, Joint Logistics Support Force of PLA, Kaiyuan, Yunnan, 661699, People's Republic of China.
Zinlin ZhaoDepartment of Radiology, No. 926 Hospital, Joint Logistics Support Force of PLA, Kaiyuan, Yunnan, 661699, People's Republic of China.
Runjun ZhangDepartment of Cardiology, No. 926 Hospital, Joint Logistics Support Force of PLA, Kaiyuan, Yunnan, 661699, People's Republic of China.
Hong BaiDepartment of Neurology, No. 926 Hospital, Joint Logistics Support Force of PLA, Kaiyuan, Yunnan, 661699, People's Republic of China.
Cong HuangDepartment of Radiology, No. 926 Hospital, Joint Logistics Support Force of PLA, Kaiyuan, Yunnan, 661699, People's Republic of China.ORCID 0000-0003-0105-672X
Yujun WangDepartment of Radiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, 310006, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebrovascular diseases (CVDs) impose a heavy global health burden, necessitating efficient management strategies. Artificial intelligence (AI) has become a key transformative tool across the CVD care continuum, and this review systematically synthesizes AI's latest advancements, limitations, and clinical translation pathways in CVD management, adhering to PRISMA-ScR guidelines. A literature search was performed in four core databases (PubMed, Web of Science, EMBASE, IEEE Xplore) for studies published between 2018-2023. After strict screening (inclusion: original research/clinical trials with clear indicators; exclusion: unvalidated studies/conference abstracts), 128 high-quality studies were included, with quality assessed via NOS and QUADAS-2. Key AI applications in CVD management include: (1) Risk prediction: Multimodal models (radiomics-CFD, EHR-imaging) achieve AUC >0.9, but performance declines in elderly patients (>75 years, ΔAUC=0.08-0.12); (2) Diagnosis: Systems like Viz LVO and DeepHemorrhage reduce LVO detection time to 6 minutes and hemorrhage segmentation Dice to 0.94, yet face false positives (3.5-5%) and workflow delays; (3) Therapeutic optimization: Intraoperative AI (eg, Siemens AI-Path) shortens microcatheter placement time by 61%, and pharmacogenomic models cut antiplatelet complications by 37%; (4) Long-term monitoring: Mobile platforms (eg, NeuroVision™) automate NIHSS scoring (ICC=0.93) but lose accuracy in home settings (ICC=0.85-0.88). Critical limitations of current AI include single-center data bias, poor interpretability, and legal risks (unclear misdiagnosis liability). This review proposes three innovative solutions: a "data-model-clinical" closed loop, a multidimensional AI value evaluation system, and defining the "human-AI collaboration boundary" in neurointerventions. Future directions focus on primary care-adapted lightweight models, comorbidity-specific algorithms, and AI-assisted rehabilitation. This review emphasizes that physician-AI collaboration and standardized frameworks (eg, AI-RADS, WHO-ITU guidelines) are critical for AI's sustainable translation in CVD care. Addressing current gaps will enable AI to further improve therapeutic efficiency and functional outcomes, alleviating the global CVD burden.

Indexed as

Artificial IntelligenceCerebrovascular DisordersDecision Support TechniquesTranslational Research, BiomedicalTranslational Science, BiomedicalClinical Decision-MakingHumansPredictive Value of TestsPrognosisRisk AssessmentRisk FactorsTreatment Outcomeartificial intelligencecerebrovascular diseasesclinical translationrisk predictionsystematic review

Identifiers

PMID41312451
PMCPMC12649784

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.