ArticleTetrahedron2025
Rearrangement of Protected Epoxy-Alcohols into Tetrahydrofuran Derivatives: The Protecting Group Matters!
Article in Tetrahedron, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Ring-Opening of Aziridines Using Tethered Hemiketals.The Journal of organic chemistry · 2026Article
- Large-Scale Rearrangement of Epoxy Esters into Tetrahydrofurans.Organic syntheses; an annual publication of satisfactory methods for the preparation of organic chemicals · 2026Article
- Single-crystal X-ray diffraction analysis and mechanistic implications of (2R*,3R*)-2-(2-phenoxyethyl)tetrahydrofuran-3-yl acetate.Acta crystallographica. Section C, Structural chemistry · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
We have explored an interesting rearrangement of protected epoxy-alcohols into tetrahydrofuran derivatives. Our protocol is operationally simple and involves treatment of a substrate with catalytic quantities of boron trifluoride diethyl etherate in methylene chloride without any special precautions to exclude air or ambient moisture. The nature of the protecting group dictates the stereochemical outcome of the cyclization. For example, with
Identifiers
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Registered trials
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