Evidence map›Paper›PMID 41312397›Full record

ArticleNew microbes and new infections2025

Genomic characterization of cefotaxime-resistant Proteobacteria isolated from a bat-harboring cave in Zambia.

Misheck Shawa, Harvey Kakoma Kamboyi, Herman Chambaro, Kyoko Hayashida, Naganori Nao, Joseph Chizimu, Mike Nundwe, Tuvshinzaya Zorigt, Naoko Kawai, Shohei Ogata and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in New microbes and new infections, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Misheck ShawaHokudai Center for Zoonosis Control in Zambia, Hokkaido University, Lusaka, 10101, Zambia.
Harvey Kakoma KamboyiDepartment of Clinical Medicine, School of Medicine, Eden University, Lusaka, Zambia.
Herman ChambaroDepartment of Pathobiology, College of Veterinary Medicine, University of Illinois Urbana-Champaign, Urbana, USA.
Kyoko HayashidaHokudai Center for Zoonosis Control in Zambia, Hokkaido University, Lusaka, 10101, Zambia.
Naganori NaoHokudai Center for Zoonosis Control in Zambia, Hokkaido University, Lusaka, 10101, Zambia.
Joseph ChizimuZambia National Public Health Institute, Ministry of Health, Lusaka, 10101, Zambia.
Mike NundweInstitute of Basic and Biomedical Sciences, Levy Mwanawasa Medical University, Lusaka, 10101, Zambia.
Tuvshinzaya ZorigtDivision of Infection and Immunity, International Institute for Zoonosis Control, Hokkaido University, N20 W10, Kita-ku, Sapporo, 001-0020, Japan.
Naoko KawaiDivision of Collaboration and Education, International Institute for Zoonosis Control, Hokkaido University, N20 W10, Kita-ku, Sapporo, 001-0020, Japan.
Shohei OgataHokudai Center for Zoonosis Control in Zambia, Hokkaido University, Lusaka, 10101, Zambia.
Joseph NdebeDivision of International Research Promotion, International Institute for Zoonosis Control, Hokkaido University, N20 W10, Kita-ku, Sapporo, 001-0020, Japan.
Mwamba NsofwaDepartment of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka, 10101, Zambia.
Msangwa SinjaniDepartment of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka, 10101, Zambia.
Situmbeko J NasileleDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Zambia, Lusaka, 10101, Zambia.
Mulemba SamutelaDepartment of Biomedical Sciences, School of Health Sciences, University of Zambia, Lusaka, 10101, Zambia.
Manyando SimbotweDepartment of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka, 10101, Zambia.
Katendi ChangulaDepartment of Para-clinical Studies, School of Veterinary Medicine, University of Zambia, Lusaka, 10101, Zambia.
Hirofumi SawaHokudai Center for Zoonosis Control in Zambia, Hokkaido University, Lusaka, 10101, Zambia.
Bernard M Hang'ombeDepartment of Para-clinical Studies, School of Veterinary Medicine, University of Zambia, Lusaka, 10101, Zambia.
Yasuhiko SuzukiHokudai Center for Zoonosis Control in Zambia, Hokkaido University, Lusaka, 10101, Zambia.
Masahiro KajiharaHokudai Center for Zoonosis Control in Zambia, Hokkaido University, Lusaka, 10101, Zambia.
Hideaki HigashiHokudai Center for Zoonosis Control in Zambia, Hokkaido University, Lusaka, 10101, Zambia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bats are widely recognized as reservoirs of emerging and re-emerging pathogens, and their ecological interactions with humans and livestock present important opportunities for the transmission of infectious agents and antimicrobial resistance (AMR). However, little is known about the occurrence of resistant bacteria in bat-associated environments in Zambia or their potential role in the maintenance of AMR outside clinical and agricultural settings. This study investigated the genomic characteristics of cefotaxime-resistant Proteobacteria isolated from bat fecal droppings collected at Leopards Hill Cave, an established hotspot for zoonotic pathogens. Four hundred bat fecal samples were cultured on cefotaxime-supplemented MacConkey agar, and those exhibiting bacterial growth were subjected to antimicrobial susceptibility testing and whole-genome analysis. Of the 400 samples processed, four (1 %) yielded growth, resulting in three bacterial species:

Indexed as

AMRBatsB. intermediaE. moriP. aeruginosaZambia

Identifiers

PMID41312397
PMCPMC12648688

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.