Evidence map›Paper›PMID 41312342›Full record

ArticleFrontiers in neurology2025

Quality of life and social support as key determinants of anxiety and depression in Myasthenia Gravis: evidence from a Chinese cohort.

Xiang Li, Zhipeng Li, Chaoyue Zhang, Long Li, Yimin Liang, Xuxiang Zhang, Fengbin Liu, Xinfeng Lin, Qilong Jiang

Abstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Silence Around Myasthenia Gravis and Mood Disorders: An Editorial Reflection.Clinical practice and epidemiology in mental health : CP & EMH · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiang Li *The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Zhipeng Li *The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Chaoyue Zhang *The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Long LiThe First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Yimin LiangThe First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Xuxiang ZhangThe First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Fengbin LiuThe First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Xinfeng LinThe First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Qilong JiangThe First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Myasthenia Gravis (MG) is a chronic autoimmune disorder frequently accompanied by anxiety and depression, which aggravate disease burden. Evidence on the relationship between clinical characteristics and psychological symptoms in MG remains inconsistent. Methods: We conducted a cross-sectional study of 93 Chinese MG patients. Clinical and demographic data were collected, and anxiety and depression were assessed using the Hospital Anxiety and Depression Scale (HADS). Associations were examined by correlation, chi-square tests, and logistic regression with false discovery rate (FDR) correction. Multivariable models adjusted for age and sex. ROC curve analyses evaluated the predictive performance of (MG Activities of Daily Living) MG-ADL, (15-item Myasthenia Gravis Quality of Life scale) MG-QOL-15, and (Social Support Rating Scale) SSRS. Results: Anxiety and depression were present in 30.1 and 35.5% of patients, respectively. In multivariable analysis, reduced quality of life (MG-QOL-15, OR = 0.85, 95% CI: 0.78-0.92, Conclusion: Psychological distress in MG is more closely linked to quality of life and social support than to conventional disease severity. Routine psychological screening with MG-QOL-15 and SSRS may facilitate early identification of high-risk patients.

Indexed as

anxietydepressiondisease severityMyasthenia Gravisquality of lifesocial support

Identifiers

PMID41312342
PMCPMC12647006

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.