Evidence map›Paper›PMID 41312225›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2025

The Variation in Practice of the Living Donor Kidney Transplant Pathway in the UK: Results of a National Survey.

Katie Nightingale, Josh Stephenson, Rajesh Sivaprakasam, Tim Brown, Nicholas Inston, Ahmed Hamsho, Rommel Ravanan, Michael Nicholson, Argiris Asderakis, Sarah Browne and 38 more

Abstract read
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

48 authors.

Katie Nightingale *Department of General Surgery, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
Josh StephensonRoyal London Hospital Transplant Department, The Royal London Hospital, Barts Health NHS Trust, London, United Kingdom.
Rajesh SivaprakasamRoyal London Hospital Transplant Department, The Royal London Hospital, Barts Health NHS Trust, London, United Kingdom.
Tim BrownRegional Nephrology and Transplant Unit, Belfast City Hospital, Belfast Health and Social Care Trust, Belfast, United Kingdom.
Nicholas InstonQueen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom.
Ahmed HamshoQueen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom.
Rommel RavananSouthmead Hospital, North Bristol NHS Trust, Bristol, United Kingdom.
Michael NicholsonDepartment of Nephrology, Urology and Renal Transplantation, Royal Free Hospital, Royal Free London NHS Foundation Trust, London, United Kingdom.
Argiris AsderakisCardiff Transplant Unit, University Hospital of Wales, Cardiff and Vale University Health Board, Cardiff, United Kingdom.
Sarah BrowneCardiff Transplant Unit, University Hospital of Wales, Cardiff and Vale University Health Board, Cardiff, United Kingdom.
James HunterUniversity Hospital Coventry, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, United Kingdom.
Lorna P MarsonEdinburgh Transplant Unit, Royal Infirmary of Edinburgh, NHS Lothian, Edinburgh, United Kingdom.
Katie L ConnorEdinburgh Transplant Unit, Royal Infirmary of Edinburgh, NHS Lothian, Edinburgh, United Kingdom.
Mortimer KelleherEdinburgh Transplant Unit, Royal Infirmary of Edinburgh, NHS Lothian, Edinburgh, United Kingdom.
Andrew SutherlandEdinburgh Transplant Unit, Royal Infirmary of Edinburgh, NHS Lothian, Edinburgh, United Kingdom.
William NortonWest of Scotland Kidney Transplant Unit, Queen Elizabeth University Hospital, NHS Greater Glasgow and Clyde, Glasgow, United Kingdom.
Hannah MapleDepartment of Transplant, Renal and Urology, Guy's Hospital, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Francis CalderDepartment of Transplant, Renal and Urology, Guy's Hospital, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Frank J M F DorRenal and Transplant Centre, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.
Adam BarlowSt James's University Hospital, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.
Imeshi WijetungaManchester Centre for Transplantation, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
Rachel YoungsSt James's University Hospital, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.
Stuart FalconerSt James's University Hospital, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.
Victoria BoardmanSt James's University Hospital, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.
Matthew Welberry SmithDepartment of Renal Medicine and Renal Transplantation, Leeds Teaching Hospitals NHS Trust, and Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Atul BagulLeicester General Hospital, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom.
Hemant SharmaRenal and Transplant Centre, Royal Liverpool University Hospital, Liverpool University Hospitals NHS Foundation Trust, Liverpool, United Kingdom.
Sanjay MehraRenal and Transplant Centre, Royal Liverpool University Hospital, Liverpool University Hospitals NHS Foundation Trust, Liverpool, United Kingdom.
Zia MoinuddinManchester Centre for Transplantation, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
Tunde CampbellManchester Centre for Transplantation, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
David van DellenManchester Centre for Transplantation, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
Alistair RogersFreeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.
Lisa BurnappNHS Blood and Transplant, Bristol, United Kingdom.
Kamran HaqSt Peter's Hospital, Ashford and St Peter's Hospitals NHS Foundation Trust, Chertsey, United Kingdom.
James YatesRenal and Transplant Unit, Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom.
Sanjay SinhaOxford Transplant Centre, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.
Shahzar MalikRoyal Devon and Exeter Hospital, Royal Devon University Healthcare NHS Foundation Trust, Exeter, United Kingdom.
Imran SaifSouthwest Transplant Centre, Derriford Hospital, University Hospitals Plymouth NHS Trust, Plymouth, United Kingdom.
Paul GibbsWessex Kidney Centre, Queen Alexandra Hospital, Portsmouth Hospitals University NHS Trust, Portsmouth, United Kingdom.
Kashuf KhanWessex Kidney Centre, Queen Alexandra Hospital, Portsmouth Hospitals University NHS Trust, Portsmouth, United Kingdom.
Rafique HarvitkarWessex Kidney Centre, Queen Alexandra Hospital, Portsmouth Hospitals University NHS Trust, Portsmouth, United Kingdom.
Badri ShresthaDepartment of Renal Transplantation, Northern General Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.
Abbas GhazanfarDepartment of Transplantation and Dialysis Access Surgery, St George's Hospital, St George's University Hospitals NHS Foundation Trust, London, United Kingdom.
Abul SiddikyDepartment of Transplantation and Dialysis Access Surgery, St George's Hospital, St George's University Hospitals NHS Foundation Trust, London, United Kingdom.
Reza MotallebzadehDepartment of Nephrology and Transplantation, Royal Free Hospital, London, United Kingdom.
Michael MonekeDepartment of Nephrology, Urology and Renal Transplantation, Royal Free Hospital, Royal Free London NHS Foundation Trust, London, United Kingdom.
Kailash Bhatia *Department of Anaesthesia and Perioperative Medicine, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
Titus Augustine *Manchester Centre for Transplantation, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Living donor kidney transplantation (LDKT) accounts for 35% of kidney transplants in the UK. The Organ Donation and Transplantation 2030 initiative underscores the necessity to enhance LDKT rates to meet growing demand. There is limited data on national variations in live donor workup pathways from initial referral to long-term follow-up. We conducted an online survey across all 23 UK transplant centres performing LDKT, covering the entire living donor pathway. We aimed to explore and highlight practice variation and identify opportunities for improvement. Responses were received from 21 centres (91.3%). Marked variation was identified in donor acceptance criteria, including age limits, body mass index thresholds, and donor evaluation timelines (6-36 weeks). Differences were also noted in multidisciplinary team processes, kidney laterality decisions, and perioperative enhanced recovery protocols. All centres used laparoscopic techniques, with hand-assisted transperitoneal nephrectomy being most common (57.1%). Donor nephrectomy and implantation were conducted sequentially in 15 (71.4%) of centres, and in parallel in six (28.6%). Variation was also seen in follow-up duration with 47.6% of centres offering lifelong follow-up. Despite excellent national outcomes, this survey highlights significant variation. Standardising key processes could streamline donor pathways, improve experiences, and support increased LDKT activity in the UK.

Indexed as

Kidney TransplantationLiving DonorsAdultFemaleHumansMaleMiddle AgedNephrectomySurveys and QuestionnairesTissue and Organ ProcurementUnited Kingdomdonor nephrectomylaparoscopyliving donor kidney transplantationperioperative carevariation

Identifiers

PMID41312225
PMCPMC12650412

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.