ArticleJournal of the Heart Valve Society
Clinical and Hemodynamic Implications of Mitral Annular Calcification.
Article in Journal of the Heart Valve Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Patient-Specific Analysis of Ventricular Vortex Formation and Flow Energetics in Rheumatic and Calcific Mitral Stenosis.Annals of biomedical engineering · 2026Article
- Massive mitral annular calcification with valvular involvement: Multimodality and longitudinal imaging correlation.Radiology case reports · 2026Article
- The Prognostic Value of Exercise Stress Echocardiography in Asymptomatic Moderate and Severe Aortic Stenosis: A Systematic Review of Stress-Derived Hemodynamic and Functional Markers.Journal of clinical medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Mitral annular calcification (MAC) is an inflammatory process that shares characteristics with atherosclerosis and results in calcium deposition in the fibrous ring supporting the mitral valve. It is commonly encountered at older ages and in people with chronic kidney disease. MAC is an important prognostic marker of adverse cardiovascular events and atrial fibrillation, as well as cardiovascular and non-cardiovascular death. When severe it can cause valvular dysfunction including mitral stenosis and/or regurgitation. Aside from effects on mitral valve function, MAC is associated with abnormal compliance of both the left atrium and left ventricle. It is also associated with disruption of normal left ventricular vortex formation and increased energy losses. In combination, these factors may help explain the symptoms of dyspnea and exercise intolerance frequently seen in MAC patients.
Indexed as
Identifiers
41312219PMC12649814What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.