ArticlemicroPublication biology2025
Opposite aging effects among cell subsets revealed in the human transcriptome and epigenome.
Article in microPublication biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
In our previous work, we reported a global landscape of opposite aging effects among mouse cell subsets, where each cell subset is defined as a combination of tissue and cell type, and aging leads to increased gene expression in one subset but reduced expression in another. In this study, we investigated whether opposite aging effects are also observed in human cell subsets using the database of differentially expressed genes (DEGs) and differentially accessible regions (DARs) in various human cell subsets. The results suggest that the opposite aging effects occur among human cell subsets at both the transcriptomic and epigenomic levels.
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