Evidence map›Paper›PMID 41311958›Full record

ArticleJACS Au2025

Crystallographic, Electronic Structure, and Computational Studies of PHOX-Ni Aryne Complexes: Origins of Regioselectivity in Metal-Bound Aryne Synthesis and Difunctionalization.

Alexander Umanzor, Nicholas A Garcia, Kevin P Quirion, Alex Lovstedt, Peng Liu, Courtney C Roberts

Abstract read
In one paragraph

Article in JACS Au, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexander UmanzorDepartment of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID https://orcid.org/0000-0001-7800-5950
Nicholas A GarciaDepartment of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID https://orcid.org/0000-0001-6809-2966
Kevin P QuirionDepartment of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.
Alex LovstedtDepartment of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID https://orcid.org/0000-0001-5812-1858
Peng LiuDepartment of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.ORCID https://orcid.org/0000-0002-8188-632X
Courtney C RobertsDepartment of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID https://orcid.org/0000-0001-8177-4013

Funding

Methods for Selective Functionalization of (Hetero)arene RingsR35GM146957 · NIGMS · UNIVERSITY OF MINNESOTA · PI Courtney C Roberts · 2022 to 2026
$1.9M
NIGMS NIH HHS R35 GM146957
6 · The paper itself

Abstract

Late transition metal aryne complexes are stable, isolable counterparts to free aryne intermediates. However, their utility has largely been limited since the Aryne Distortion Model (ADM) cannot be applied to substituted aryne complex reactivity, leading to nonselective reactions. Our group recently reported the first regioselective synthesis and difunctionalization of a CyPHOX-Ni

Indexed as

arynesnickelPHOX ligandsregioselectivityselectivity models

Identifiers

PMID41311958
PMCPMC12648280

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.