Evidence map›Paper›PMID 41311919›Full record

ArticleOpen forum infectious diseases2025

Immunodeficiency, HIV Viremia, and Incident Anal Cancer Among People With HIV in South Africa.

Nathalie V Fernández Villalobos, Yann Ruffieux, Chido Chinogurei, Andreas D Haas, Nicola Low, Matthias Egger, Jenni Noble, Naomi Folb, Gary Maartens, Eliane Rohner

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nathalie V Fernández VillalobosInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0001-7560-5256
Yann RuffieuxInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0002-0891-2448
Chido ChinogureiCentre for Integrated Data and Epidemiological Research, School of Public Health, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-1560-7580
Andreas D HaasInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0002-4849-181X
Nicola LowInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0003-4817-8986
Matthias EggerCentre for Integrated Data and Epidemiological Research, School of Public Health, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0001-7462-5132
Jenni NobleMedscheme, Cape Town, South Africa.
Naomi FolbMedscheme, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-2667-0956
Gary MaartensDivision of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0003-3080-6606
Eliane RohnerInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0002-0554-2875

Funding

Observational Antiretroviral Studies In Southern Africa (OASIS) CollaborationU01AI069924 · NIAID · UNIVERSITAT BERN · PI Cleophas Chimbetete, Mary-Ann Davies · 2006 to 2026
$55.9M
NIAID NIH HHS U01 AI069924
6 · The paper itself

Abstract

Among 130 992 people with HIV (PWH) in South Africa, 60 anal cancers were diagnosed. Lower CD4 counts and, to a lesser extent, higher HIV RNA viral loads were associated with an increased anal cancer risk. Maintaining high CD4 counts may contribute to anal cancer prevention among PWH in South Africa.

Indexed as

Anal cancerCD4 cell countHIVimmunodeficiencySouth Africaviral load

Identifiers

PMID41311919
PMCPMC12651545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.