ArticleFrontiers in pharmacology2025
Molecular genetic basis of the primary emotions in young adults: an exploratory analysis of genetic polymorphisms across dopamine, serotonin, oxytocin, endogenous opioid, and neurotrophic factor pathways.
Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Advances in affective neuroscience have unraveled the neurobiological underpinnings of primary emotions, making them suitable candidates for molecular genetic research. The aim of this study was to perform an exploratory molecular genetic association analysis of primary emotions in humans. Methods: A total of 333 young adults ( Results: Our findings revealed several significant and nominally significant associations between genetic polymorphisms and primary emotions which showed a clear sex-specific pattern. In males, associations were found with the Discussion: Overall, the present study identified several novel candidate genes which might be related to primary emotions in a sample of young adults. Although our findings should be considered preliminary, they may have important implications for personality research as well as clinical practice.
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