ArticleCureus2025
Sarcomatoid Lung Carcinoma Successfully Treated With Combined Cytotoxic Chemotherapy and Anti-Programmed Death-Ligand 1 (Anti-PD-L1) Antibodies.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pulmonary sarcomatoid carcinoma is a rare, aggressive subtype of non-small-cell lung cancer with a poor prognosis and no established standard therapy for advanced disease. We report the case of a 68-year-old man with stage IVB pleomorphic carcinoma whose tumor expressed programmed death-ligand 1 (PD-L1) with a tumor proportion score of 25%. The patient received four cycles of first-line therapy combining atezolizumab with carboplatin and paclitaxel. This treatment resulted in a significant partial response, with marked shrinkage of the primary tumor and metastatic lesions. This case suggests that the combination of an anti-PD-L1 antibody and platinum-based chemotherapy is a promising and effective therapeutic strategy for this challenging malignancy.
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