ArticleJOR spine2025
Evaluation of Lumbar Intervertebral Disc and Facet Joint Degeneration Using Histogram Analysis of T2 and T2* Values.
Article in JOR spine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Lumbar facet joint (LFJ) and intervertebral disc (IVD) degeneration are the common causes of low back pain. The aim of this study is to explore the feasibility of histogram analysis of T2 and T2* values on grading LFJ and IVD degeneration and to examine the correlation between the LFJ and IVD in the degenerative process. Methods: 420 IVDs and 840 LFJs of 87 subjects were examined using T2WI, T2 and T2* mapping. All IVDs and LFJs were classified, respectively, according to the Pfirrmann and Weishaupt grade and grouped by patient age. Histogram-derived parameters based on T2 (T2-HPs) and T2* (T2*-HPs) values of IVDs and LFJs were compared among the different groups. Results: The interobserver agreement for Pfirrmann grade was good ( Conclusions: Histogram analysis of T2/T2* values is feasible for detecting IVD degeneration, but the feasibility of grading LFJ is still controversial. The DI of LFJ is higher than that of IVD under 39 years old, challenging the commonly accepted paradigm of the degenerative process beginning at the IVDs.
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