Evidence map›Paper›PMID 41311451›Full record

ArticleOxford medical case reports2025

Plasma exchange as an effective treatment for refractory pure red cell aplasia post-ABO-incompatible hematopoietic stem cell transplantation: a rare complication.

Asaad A Khalaf, Mohammed Al Farttoosi, Sajjad Ghanim Al-Badri, Abbas Hamza Abbas, Riyam Mudheher Nabbat Al-Ajrash, Ahmed Shamil Hashim, Zaryab Bacha

Abstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Asaad A KhalafConsultant hematologist, Basrah Health Directorate, Basrah, Iraq.
Mohammed Al FarttoosiCollege of Medicine, University of Basrah, Basrah, Iraq.
Sajjad Ghanim Al-BadriCollege of Medicine, University of Warith Al-Anbiyaa, Karbala, Iraq.ORCID https://orcid.org/0009-0003-6259-1045
Abbas Hamza AbbasCollege of Medicine, University of Basrah, Basrah, Iraq.ORCID https://orcid.org/0009-0004-3722-702X
Riyam Mudheher Nabbat Al-AjrashAL-Yarmook teaching hospital, Baghdad, Iraq.
Ahmed Shamil HashimUniversity of Baghdad, College of Medicine, Baghdad, Iraq.
Zaryab BachaKhyber Medical College, Peshawar, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pure red blood cell aplasia (PRCA) is a rare complication of major ABO-incompatible hematopoietic stem cell transplantation (HSCT), characterized by severe anemia due to impaired erythropoiesis. We report the case of 52 year old man with chronic myeloid leukemia who developed refractory PRCA four months post transplant. The patient was unresponsive to multiple immunosuppressive agents but showed marked hematologic recovery following ten sessions of plasma exchange (PEX) over five weeks. Hemoglobine level rose from 6 g/Dl to 16 g/dL, eliminating the need for further transfusions. This report highlights a case of refractory PRCA successfully treated with PEX, underscoring its potential efficacy and the need for further research to establish treatment guidelines.

Indexed as

ABO-incompatible HSCThematopoietic stem cell transplantationpure red cell aplasiared cell engraftmentrefractory AnemiaTheraputic plasma exchange

Identifiers

PMID41311451
PMCPMC12648554

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.