Evidence map›Paper›PMID 41311259›Full record

ArticleInternational journal of technology assessment in health care2025

Value-based health care frameworks for the health technology assessments of "omics" technologies: an international survey.

Tommaso Osti, Abdelrahman Taha, Eva Reviriego-Rodrigo, Roberta Pastorino, Stefania Boccia, Iñaki Gutierrez-Ibarluzea

Abstract read
In one paragraph

Article in International journal of technology assessment in health care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tommaso OstiDepartment of Life Sciences and Public Health, Section of Hygiene, https://ror.org/03h7r5v07Universita Cattolica del Sacro Cuore, Rome, Italy.ORCID https://orcid.org/0000-0003-1029-9539
Abdelrahman TahaDepartment of Life Sciences and Public Health, Section of Hygiene, https://ror.org/03h7r5v07Universita Cattolica del Sacro Cuore, Rome, Italy.
Eva Reviriego-RodrigoBasque Office for Health Technology Assessment, BIOEF, https://ror.org/054hj6489Basque Foundation for Health Innovation and Research, Barakaldo, Spain.ORCID https://orcid.org/0000-0002-0420-8816
Roberta PastorinoDepartment of Life Sciences and Public Health, Section of Hygiene, https://ror.org/03h7r5v07Universita Cattolica del Sacro Cuore, Rome, Italy.
Stefania BocciaDepartment of Life Sciences and Public Health, Section of Hygiene, https://ror.org/03h7r5v07Universita Cattolica del Sacro Cuore, Rome, Italy.
Iñaki Gutierrez-IbarluzeaBasque Office for Health Technology Assessment, BIOEF, https://ror.org/054hj6489Basque Foundation for Health Innovation and Research, Barakaldo, Spain.ORCID https://orcid.org/0000-0002-4080-7963

Funding

HORIZON EUROPE Marie Sklodowska-Curie Actions 823995
6 · The paper itself

Abstract

backgroundDespite omics technologies gaining traction in clinical settings, particularly in oncology, challenges persist in their widespread adoption due to the pre-requisite robust evidence supporting efficacy and cost-effectiveness. This study aims to explore the experiences of organizations working in the health technology assessment (HTA) field in evaluating omics technologies, with a particular focus on the adoption and application of specific assessment frameworks.

methodsWe conducted a global survey to gather insights into current practices and frameworks used in HTA evaluations of omics technologies.

resultsWe gathered responses from thirty-nine participants representing organizations across twenty-nine countries and five continents. Among them, 51 percent (n = 20) reported experience in evaluating omics technologies, including multi-omics tests for early disease detection, biomarker-based cancer diagnostics, and advanced genomic sequencing techniques. Only three organizations employed specific assessment frameworks: the DISCUSSION: Despite their relevance, the limited adoption of tailored frameworks highlights the need for more structured and context-specific approaches to facilitate the integration of omics technologies into healthcare systems. Collaborative efforts among stakeholders, including patients, healthcare providers, policymakers, and industry representatives, are crucial for devising robust evaluation strategies addressing the complexities of omics technologies comprehensively.

Indexed as

GenomicsTechnology Assessment, BiomedicalCost-Benefit AnalysisHumansInternationalitySurveys and QuestionnairesValue-Based Health Careassessment frameworkgenomicshealth technology assessmentpersonalised medicineprecision medicinevalue-based healthcare

Identifiers

PMID41311259
PMCPMC12689241

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.