Evidence map›Paper›PMID 41311216›Full record

ArticleActa biochimica et biophysica Sinica2025

Antibody-oligonucleotide conjugates for spatial proteomics: principles, applications, and challenges.

Yinghui Qiu, Chunlan Li, Peiying Ye, Haiyun Zhang, Yanxiu Liu, Weiyan Ma, Chen Lin, Rongqin Ke

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta biochimica et biophysica Sinica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yinghui QiuSchool of Medicine, Huaqiao University, Xiamen 362021, China.
Chunlan LiSchool of Medicine, Huaqiao University, Xiamen 362021, China.
Peiying YeSchool of Medicine, Huaqiao University, Xiamen 362021, China.
Haiyun ZhangDepartment of Thoracic Surgery, Xiamen Chang Gung Memorial Hospital, Xiamen 361000, China.
Yanxiu LiuSchool of Medicine, Huaqiao University, Xiamen 362021, China.
Weiyan MaSchool of Medicine, Huaqiao University, Xiamen 362021, China.
Chen LinSchool of Medicine, Huaqiao University, Xiamen 362021, China.
Rongqin KeSchool of Medicine, Huaqiao University, Xiamen 362021, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spatial biology aims to elucidate cellular organization, function, and interactions within native tissue contexts, offering key insights into both normal physiology and disease. Spatial proteomics complements this by enabling high-resolution mapping of protein localization and abundance, directly reflecting functional cellular states. Unlike transcriptomics, which infers potential activity, proteomics captures actual molecular functions, including post-translational modifications and dynamic interactions. However,

Indexed as

antibody-oligonucleotide conjugatesmulti-omicsspatial proteomicstissue microenvironment

Identifiers

PMID41311216
PMCPMC13191458

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.