Evidence map›Paper›PMID 41311101›Full record

ArticleEpilepsia open2025

How to report neurotechnology and artificial intelligence studies in epilepsy: Peer-review-inspired recommendations.

Pedro F Viana, Matthew McWilliam, Andrea Biondi, Jesus Servando Medel-Matus, Naoto Kuroda, Giulia Sofia Cereda, Aristea S Galanopoulou

Abstract read
In one paragraph

Article in Epilepsia open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pedro F VianaInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID https://orcid.org/0000-0003-0861-8705
Matthew McWilliamInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID https://orcid.org/0009-0009-4325-3941
Andrea BiondiInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID https://orcid.org/0000-0003-1072-665X
Jesus Servando Medel-MatusDepartment of Pediatrics, Neurology Division, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, USA.ORCID https://orcid.org/0000-0003-1103-468X
Naoto KurodaDepartment of Pediatrics, Wayne State University, Detroit, Michigan, USA.ORCID https://orcid.org/0000-0003-1977-4893
Giulia Sofia CeredaEpilepsy Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Aristea S GalanopoulouSaul R. Korey Department of Neurology, Isabelle Rapin Division of Child Neurology, Dominick P. Purpura Department of Neuroscience, Laboratory of Developmental Epilepsy, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID https://orcid.org/0000-0002-0472-2903

Funding

The Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx) Public Engagement CoreU54NS100064 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ENGEL, JEROME NONE, GALANOPOULOU, ARISTEA S · 2017 to 2021
$21.7M
Translational Platform for Epilepsy Therapy and Biomarker DiscoveryR01NS127524 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Denes V. Agoston, LISA D COLES · 2022 to 2026
$11.0M
SUPPORT FOR THE ROSE F KENNEDY IDDRC P50P50HD105352 · NICHD · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI SOPHIE MOLHOLM, Steven Upshaw Walkley · 2021 to 2026
$7.0M
Abbe Goldstein/Joshua Lurie and Laurie Marsh/Dan Levitz familiesHeffer Family and the Segal Family FoundationsIsabelle Rapin Family FoundationNational Institute for Health and Care Research NIHR305718NICHD NIH HHS P50 HD105352NINDS NIH HHS R01 NS127524NINDS NIH HHS U54 NS100064Rose F. Kennedy Intellectual and Developmental Disabilities Research Center RFK-IDDRCU.S. Department of Defense HT9425-24-1-0134U.S. Department of Defense W81XWH-22-1-0210U.S. Department of Defense W81XWH-22-1-0510
6 · The paper itself

Abstract

objectiveThe integration of neurotechnology and artificial intelligence (AI) in epilepsy research has led to significant advancements in diagnosis, monitoring, and treatment. However, the impact of these innovations is often diminished by inadequate and inaccurate reporting, limiting their reproducibility and implementation. This study aimed to identify common peer review concerns and develop reporting recommendations specific to neurotechnology and AI studies in epilepsy.

methodsWe conducted a qualitative analysis of peer review comments from original research article submissions to Epilepsia Open over a 2-year period (September 2021-August 2023). We selected manuscripts that focused on neurotechnology or AI applications in epilepsy, excluding those using standard clinical technologies or conventional statistical analyses. Reviewer comments were classified using a validated checklist, categorizing issues into themes and subthemes. Based on recurrent peer review concerns, we developed a set of reporting recommendations for neurotechnology and AI studies.

resultsAmong 329 manuscripts sent for peer review, 67 were classified as neurotechnology or AI studies and included in the analysis. These studies predominantly involved advanced neuroimaging analysis, advanced electroencephalography (EEG) analysis, and neuromodulation systems. Reviewer comments were primarily focused on study methodology (37%), manuscript presentation (19%), discussion (17%), and results (12%). Based on peer review comments, we formulated reporting recommendations, hoping to enhance study transparency, methodological rigor, and reproducibility. SIGNIFICANCE: Our reporting recommendations address key concerns raised during peer review, providing guidance to authors and reviewers to improve the quality and clarity of neurotechnology and AI research in epilepsy. These recommendations complement existing reporting standards and contribute to the advancement of robust and impactful research in the field. PLAIN LANGUAGE SUMMARY: We studied how researchers report studies on neurotechnology and AI in epilepsy. Many studies face problems during peer review, such as unclear methods, weak study rationale, and errors in statistics or citations. We analyzed reviewer feedback and created recommendations to improve how these studies are reported. Our goal is to help researchers develop and present their work more clearly and accurately, making it easier for others to understand and build upon their findings. This can lead to better use of AI and neurotechnology in epilepsy research and care.

Indexed as

artificial intelligenceepilepsymachine learningneurotechnologystandards

Identifiers

PMID41311101
PMCPMC13394119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.