Evidence map›Paper›PMID 41310751›Full record

Observational studyArthritis research & therapy2025

Bedside needle arthroscopy for native joint bacterial arthritis in a real-world clinical practice setting: a prospective cohort study.

Alex B Walinga, Stein J Janssen, Tobias Stornebrink, Rover Krips, Sander W Tas, Arthur J Kievit, Gino M M J Kerkhoffs

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Arthritis research & therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alex B WalingaDepartment of Orthopedic Surgery and Sports Medicine, Amsterdam University Medical Center/University of Amsterdam University of Amsterdam, Meibergdreef 9, Amsterdam, 1105AZ, The Netherlands. a.b.walinga@amsterdamumc.nl.
Stein J JanssenDepartment of Orthopedic Surgery and Sports Medicine, Amsterdam University Medical Center/University of Amsterdam University of Amsterdam, Meibergdreef 9, Amsterdam, 1105AZ, The Netherlands.
Tobias StornebrinkDepartment of Orthopedic Surgery and Sports Medicine, Amsterdam University Medical Center/University of Amsterdam University of Amsterdam, Meibergdreef 9, Amsterdam, 1105AZ, The Netherlands.
Rover KripsDepartment of Orthopedic Surgery, Flevoziekenhuis, Almere, The Netherlands.
Sander W TasDepartment of Rheumatology and Clinical Immunology, Amsterdam Rheumatology and Immunology Center, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, The Netherlands.
Arthur J KievitDepartment of Orthopedic Surgery and Sports Medicine, Amsterdam University Medical Center/University of Amsterdam University of Amsterdam, Meibergdreef 9, Amsterdam, 1105AZ, The Netherlands.
Gino M M J KerkhoffsDepartment of Orthopedic Surgery and Sports Medicine, Amsterdam University Medical Center/University of Amsterdam University of Amsterdam, Meibergdreef 9, Amsterdam, 1105AZ, The Netherlands. g.m.kerkhoffs@amsterdamumc.nl.

Funding

Amsterdam UMC - Innovation 2021-43Arthrex GmbH IIRR-01361
6 · The paper itself

Abstract

backgroundBacterial (i.e., septic) arthritis requires prompt source control, including drainage of the infected synovial fluid, often through arthrocentesis (needle aspiration) or surgical intervention, in combination with antibiotics to prevent joint damage; however, when surgical intervention is required, conventional arthroscopy can lead to treatment delays and anesthesia-related complications. To overcome these delays, needle arthroscopy was recently developed to offer the possibility of 2-mm diameter arthroscopy lavage under local anesthesia. The purpose of this study was to prospectively evaluate bedside needle arthroscopy under local anesthesia to demonstrate its potential as an effective, minimally invasive alternative for timely diagnosis and joint lavage in patients with (suspected) native bacterial arthritis in a real-world clinical practice setting.

methodsOver a 30-month period, this prospective, double center cohort study included patients with either confirmed (positive synovial fluid culture) or highly suspected (≥ 2 local signs and ≥ 1 systemic sign) native joint bacterial arthritis. The primary outcome was the need for reoperation (conventional arthroscopy or arthrotomy) within 30 days. Bivariate analysis assessed differences in patient and treatment characteristics between successful and failed needle arthroscopic debridement.

resultsForty-two patients (44 native joints) underwent needle arthroscopy. The mean age was 67 years (SD 16), the mean BMI was 26.8 kg/m

conclusionsA single bedside needle arthroscopy was effective in treating 86% of patients with confirmed or suspected native joint bacterial arthritis in a real-world practice, avoiding the need for general anesthesia or conventional surgery. This approach represents a safe and effective, minimally invasive alternative that can be rapidly implemented, enabling early joint lavage and potentially reducing the risk of secondary osteoarthritis.

trial registrationWe pre-registered this trial on the Dutch Trial Register, later called CCMO (NTR 21076, CCMO NL78387.018.21).

Indexed as

Arthritis, InfectiousArthroscopyPoint-of-Care SystemsAgedAged, 80 and overCohort StudiesFemaleHumansMaleMiddle AgedNeedlesProspective StudiesSynovial FluidTreatment OutcomeBacterial arthritisBedsideFailure rateLocal anesthesiaNanoneedleNanoscopeNeedle arthroscopyReoperationSeptic arthritis

Identifiers

PMID41310751
PMCPMC12763899

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.