Evidence map›Paper›PMID 41310745›Full record

ArticleTrials2025

Study protocol for a randomized controlled trial assessing the effect of lateral position intubation on bronchial blocker placement during unilateral video-assisted thoracic surgery.

Zhengduo Zhang, Xi Liu, Xi Zhang, Bei Zhou, Yawen Tang, Fei Tong, Yonghe Hu, Feifan Liu, Siping Hu, He Liu and 1 more

Abstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhengduo Zhang *Department of Anesthesiology & Clinical Research Center for Anesthesia and Perioperative Medicine & Key Laboratory of Anesthesia and Analgesia Application Technology, Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang, Chinese Medical University, Huzhou, China.
Xi Liu *Department of Anesthesiology, Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou, China.
Xi Zhang *School of Brain Science and Brain Medicine, Zhejiang University School of Medicine, Hangzhou, China.
Bei Zhou *Department of Anesthesiology & Clinical Research Center for Anesthesia and Perioperative Medicine & Key Laboratory of Anesthesia and Analgesia Application Technology, Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang, Chinese Medical University, Huzhou, China.
Yawen TangDepartment of Anesthesiology & Clinical Research Center for Anesthesia and Perioperative Medicine & Key Laboratory of Anesthesia and Analgesia Application Technology, Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang, Chinese Medical University, Huzhou, China.
Fei TongDepartment of Anesthesiology & Clinical Research Center for Anesthesia and Perioperative Medicine & Key Laboratory of Anesthesia and Analgesia Application Technology, Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang, Chinese Medical University, Huzhou, China.
Yonghe HuDepartment of Anesthesiology & Clinical Research Center for Anesthesia and Perioperative Medicine & Key Laboratory of Anesthesia and Analgesia Application Technology, Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang, Chinese Medical University, Huzhou, China.
Feifan LiuDepartment of Anesthesiology & Clinical Research Center for Anesthesia and Perioperative Medicine & Key Laboratory of Anesthesia and Analgesia Application Technology, Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang, Chinese Medical University, Huzhou, China.
Siping HuDepartment of Anesthesiology & Clinical Research Center for Anesthesia and Perioperative Medicine & Key Laboratory of Anesthesia and Analgesia Application Technology, Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang, Chinese Medical University, Huzhou, China. hsp0526@163.com.
He LiuDepartment of Anesthesiology & Clinical Research Center for Anesthesia and Perioperative Medicine & Key Laboratory of Anesthesia and Analgesia Application Technology, Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang, Chinese Medical University, Huzhou, China. lh121061@163.com.
Huijuan TanDepartment of Clinical Pharmacy, Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang, Chinese Medical University, Huzhou, China. tanhuijuan1987@163.com.ORCID http://orcid.org/0009-0004-4357-7106

Funding

Medical Science and Technology Project of Zhejiang Province 2020ZH043Natural Science Foundation of Zhejiang Province LY21H090001
6 · The paper itself

Abstract

backgroundApproximately one-third of patients who undergo bronchial blocker (BB) intubation in the conventional supine position suffer BB malposition. This trial aims to explore the efficiency and clinical application of BB intubation in the lateral position to reduce the incidence of BB malposition in patients undergoing video-assisted thoracic surgery (VATS).

methodsThis single-center, parallel-group, randomized controlled trial will enroll 110 patients aged 18-80 years who are scheduled for elective unilateral VATS with BB intubation under general anesthesia. Participants will be randomly assigned (1:1) to either the lateral BB intubation group or the conventional supine BB intubation group. The primary outcome is the incidence of BB malposition observed by fiberoptic bronchoscopy (FOB). Secondary outcomes include the duration of intubation, the frequency and duration of FOB usage, whether to re-intubate, intraoperative vital signs, and postoperative recovery. DISCUSSION: This trial will confirm the clinical efficacy and superiority of BB intubation in the lateral position to consolidate the lateral intubation pattern in thoracic anesthesia. We expect that performing lateral BB intubation can reduce the BB malposition rate and result in more stable intraoperative vital signs and fewer postoperative complications, which is in line with the concept of Enhanced Recovery After Surgery in thoracic anesthesia.

trial registrationChinese Clinical Trial Registry ChiCTR2400081961. Registered on March 18, 2024.

Indexed as

Intubation, IntratrachealPatient PositioningThoracic Surgery, Video-AssistedAdolescentAdultAgedAged, 80 and overAnesthesia, GeneralBronchoscopyEquivalence Trials as TopicFemaleFiber Optic TechnologyHumansMaleMiddle AgedRandomized Controlled Trials as TopicBronchial blockerIntratracheal intubationLateral positionMalpositionVideo-assisted thoracic surgery

Identifiers

PMID41310745
PMCPMC12659280

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.