Evidence map›Paper›PMID 41310660›Full record

ArticleHead & face medicine2025

Measurement of three-dimensional facial changes after orthodontic extraction: a retrospective longitudinal study.

Weiqiang Wu, Yu Wang, Wenhsuan Lu, Jiale Yan, Jade Teng, Lanxi Nie, Yao Tang, Bing Han, Si Chen, Yuning Zhang and 3 more

Abstract read
In one paragraph

Article in Head & face medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Weiqiang Wu *Department of Orthodontics, Cranial-Facial Growth and Development Center, Peking University School and Hospital of Stomatology, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, People's Republic of China.
Yu Wang *Department of Orthodontics, Cranial-Facial Growth and Development Center, Peking University School and Hospital of Stomatology, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, People's Republic of China.
Wenhsuan Lu *Department of Orthodontics, Cranial-Facial Growth and Development Center, Peking University School and Hospital of Stomatology, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, People's Republic of China.
Jiale Yan *Department of Orthodontics, Cranial-Facial Growth and Development Center, Peking University School and Hospital of Stomatology, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, People's Republic of China.
Jade TengDepartment of Orthodontics, Cranial-Facial Growth and Development Center, Peking University School and Hospital of Stomatology, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, People's Republic of China.
Lanxi NieDepartment of Orthodontics, Cranial-Facial Growth and Development Center, Peking University School and Hospital of Stomatology, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, People's Republic of China.
Yao TangSchool of Stomatology, Zhejiang Provincial Clinical Research Center for Oral Diseases, Stomatology HospitalZhejiang University School of MedicineKey Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, 310006, China.
Bing HanDepartment of Orthodontics, Cranial-Facial Growth and Development Center, Peking University School and Hospital of Stomatology, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, People's Republic of China. kqbinghan@bjmu.edu.cn.ORCID http://orcid.org/0000-0003-4584-1092
Si ChenDepartment of Orthodontics, Cranial-Facial Growth and Development Center, Peking University School and Hospital of Stomatology, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, People's Republic of China.
Yuning ZhangDepartment of Orthodontics, Cranial-Facial Growth and Development Center, Peking University School and Hospital of Stomatology, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, People's Republic of China.
Wei LiangDepartment of Orthodontics, Cranial-Facial Growth and Development Center, Peking University School and Hospital of Stomatology, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, People's Republic of China. bmuliang@bjmu.edu.cn.ORCID http://orcid.org/0000-0002-5447-678X
Xiaomo LiuDepartment of Orthodontics, Cranial-Facial Growth and Development Center, Peking University School and Hospital of Stomatology, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, People's Republic of China. momo96@163.com.
Yunfan ZhangNational Center for Stomatology &Biomaterials and Digital Medical Devices & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health &NMPA Key Laboratory for Dental Materials, National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral, Beijing, 100081, People's Republic of China. YunfanZhang@bjmu.edu.cn.

Funding

Beijing Research Ward Excellence Program BRWEP2024W194100100China Postdoctoral Science Foundation 2022M710257Clinical Research Foundation of Peking University School and Hospital of Stomatology PKUSS-2023CRF301National Key Research and Development Program of China 2024YFC2510700National Natural Science Foundation of China 82225012Natural Science Foundation of Beijing Municipality L242037, L222001The Program for New Clinical Techniques and Therapies of Peking University School and Hospital of Stomatology PKUSSNCT-25B11Young Elite Scientist Sponsorship Program by CAST 2022QNRC001
6 · The paper itself

Abstract

backgroundThis study aimed to assess the three-dimensional facial morphological changes and acquire quantitative relationship between facial landmarks and zygion point to analyze the overall facial soft tissue impact of extraction and non-extraction orthodontic treatment.

methodsA total of 21 extraction (19.5 ± 9.2 years) and 21 non-extraction (26.2 ± 9.1 years) versus consecutive patients were enrolled. The pretreatment and posttreatment 3D facial scans were captured using the FaceSCAN3D optical system. After establishing the coordinate system and manually placing landmark, fourteen linear and twelve angular measurements were obtained. Additionally, sixteen projection distances between landmarks and the Zygion point were measured. Color-coded displacement maps were conducted through surface registration for visualization and qualitatively assessed facial changes.

resultsIn extraction group, inter-cheek width (2.60 ± 5.64 mm, P = 0.050) and mouth width (1.92 ± 3.89 mm, P = 0.040) increased, while upper lip fullness (-0.88 ± 1.11 mm, P = 0.003), lower lip fullness(-0.55 ± 1.21 mm, P = 0.050), and Li-N'-Pg' angle (-1.55 ± 1.09°, P < 0.001) decreased (T1-T0). As for quantitative measurements, the backward movement of landmarks in paranasal area (bilateral Al [nasal ala]: -1.14 ± 1.84 mm and -1.14 ± 1.47 mm, P = 0.010 and P = 0.002, respectively; bilateral Subal [subnasal ala]: -1.23 ± 2.18 mm and -1.25 ± 1.46 mm, P = 0.018 and P = 0.001, respectively) was observed. In the cheek area, significant changes were found in: left Ck-i [cheek-inner]: -1.40 ± 2.18 mm, P = 0.008; right Ck-m (cheek-middle): -2.32 ± 2.71 mm, P = 0.001), right Ck-o [cheek-outer]: -2.65 ± 4.05 mm, P = 0.007). In the lip area, changes were noted in: (bilateral Chp [chresta philtri]: P < 0.001, bilateral Ch [cheilion]: P < 0.001, Ls (labrale superius]: P = 0.002, Stm [stomion]: P < 0.001, and Li [labrale inferius]: P = 0.002. All changes observed were measured relative to the Zygion point in extraction group.

conclusionsThis study reveals the effects of extraction and non-extraction treatments on the lip, cheek and paranasal areas. Significant differences were found in the linear and angular measurements. The lower lip retraction was more pronounced in the extraction group. A new quantitative method for measuring facial landmarks was established. Inward and downward movement of facial landmarks was observed after extraction treatment.

trial registrationThe protocol of this study (PKUSSIRB-202392145) was registered at the Chinese Clinical Trial Registry (Chictr.org.cn) with the identifier ChiCTR2000034288 (01/07/2020).

Indexed as

FaceImaging, Three-DimensionalOrthodontics, CorrectiveTooth ExtractionAdolescentAdultAnatomic LandmarksCephalometryFemaleHumansLongitudinal StudiesMaleRetrospective StudiesYoung AdultExtractionOrthodontic treatmentSoft tissueThree‐dimensional scan

Identifiers

PMID41310660
PMCPMC12659569

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.