Evidence map›Paper›PMID 41310584›Full record

ArticleBMC medical informatics and decision making2025

Eye-XAI: an explainable artificial intelligence approach for eye disease detection using symptom analysis.

Ahmed Al Marouf, Md Mozaharul Mottalib, Sadia Sobhana Ridi, Omar Jafarullah, Jon Rokne, Reda Alhajj

Abstract read
In one paragraph

Article in BMC medical informatics and decision making, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ahmed Al MaroufDepartment of Computer Science, University of Calgary, 2500, University Drive, Calgary, Alberta, T2N 1N4, Canada. ahmedal.marouf@ucalgary.ca.
Md Mozaharul MottalibDepartment of Computer and Information Sciences, University of Delaware, 18 Amstel Ave, Newark, Delaware, DE 19716, USA.
Sadia Sobhana RidiDepartment of Computer Science and Engineering, Brac University, 224 Bir Uttam Rafiqul Islam Ave, Dhaka, 1212, Bangladesh.
Omar JafarullahIspahani Islamia Eye Institute and Hospital, 116/C/2, Monipuripara, Farmgate, Dhaka, 1215, Bangladesh.
Jon RokneDepartment of Computer Science, University of Calgary, 2500, University Drive, Calgary, Alberta, T2N 1N4, Canada.
Reda AlhajjDepartment of Computer Science, University of Calgary, 2500, University Drive, Calgary, Alberta, T2N 1N4, Canada. alhajj@ucalgary.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The early and accurate detection of eye diseases play a pivotal role in preventing vision loss and improving patients’ quality of life. It is therefore important to search for methods for improving this detection. It turns out that Artificial Intelligence (AI) has shown great promise for the detection task. However, AI models are often opaque and complex and as a result there has been a slow adoption for these models in clinical settings. In this paper Eye-XAI is introduced which provides an effective approach to the detection combining Explainable Artificial Intelligence (XAI) techniques with symptom analysis to enhance the transparency and interpretability of eye disease detection models. Our results demonstrate that Eye-XAI not only achieves high accuracy (99.11%) for eye disease detection but also provides transparent and interpretable insights into the diagnostic process. The adoption of Eye-XAI can therefore significantly enhance the early detection and management of eye diseases while empowering clinicians with a deeper understanding of its AI-based diagnostic recommendations. Furthermore, this approach promotes patient engagement by facilitating communication and trust between patients and their healthcare providers. Eye-XAI represents a major step towards the integration of XAI in ophthalmology, unlocking new possibilities for improved eye disease diagnosis and treatment.

Indexed as

Artificial IntelligenceEye DiseasesSymptom AssessmentHumansExplainable artificial intelligenceEye diseaseMachine learningSHAPSymptom analysisXGBoost

Identifiers

PMID41310584
PMCPMC12659348

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.