ArticleBMC ophthalmology2025
Effect of mydriasis on anterior segment biometric parameters of patients with age-related cataracts.
Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Mathematical Modeling of IOL Power Changes After Pupil Dilation Based on Multifactorial Analysis.Journal of ophthalmology · 2026Article
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7 authors.
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Abstract
purposeTo determine the risk of mydriasis-induced angle closure in patients with intumescent age-related cataracts with different anterior chamber angle widths through a comparative analysis of anterior segment biometric parameters before and after mydriasis.
methodsA total of 195 patients with cortical intumescent cataracts were grouped into four according to the mean TIA in the four quadrants before mydriasis as follows: extremely narrow-angle group, 0° < TIA ≤ 10°; narrow-angle group, 10° < TIA ≤ 20°; wide-angle group, 20° < TIA ≤ 30°; and ultra-wide-angle group, TIA > 30°. The biological parameters obtained with UBM before and after mydriasis were compared.
resultsFor the extremely narrow-angle group, the TIA and AOD500 values could increase or decrease after mydriasis, indicating that the anterior chamber angle could widen or narrow, and there was a slight but statistically significant increase in IOP after dilation. For the other groups, the AOD500 and TIA significantly increased after mydriasis, signifying a more open anterior chamber angle.
conclusionPatients with 0° < TIA ≤ 10° have a high risk of angle closure and should undergo laser peripheral iridotomy before mydriasis to prevent acute elevation of intraocular pressure. Patients with 10° < TIA ≤ 20° have a low risk, and they can undergo routine mydriasis, but changes in their anterior chamber morphology should be closely monitored. When TIA > 20°, the risk is almost negligible, and mydriasis can be safely induced.
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