Evidence map›Paper›PMID 41310104›Full record

ArticleExperimental & molecular medicine2025

H3K18 lactylation in cancer-associated fibroblasts drives malignant pleural effusion progression via TNFR2

Linlin Ye, Xuan Xiang, Zihao Wang, Siyu Zhang, Qianqian Xue, Xiaoshan Wei, Yao Liu, Haolei Wang, Jiaqi Ai, Bohan Yang and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental & molecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Multiomics analysis reveals that senescent CXCL16Journal of translational medicine · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Linlin Ye *Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xuan Xiang *Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zihao Wang *Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Siyu Zhang *Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Qianqian XueDepartment of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xiaoshan WeiDepartment of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yao LiuDepartment of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Haolei WangDepartment of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jiaqi AiDepartment of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Bohan YangDepartment of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Long ChenDepartment of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yiran NiuDepartment of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wenbei PengDepartment of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. pengwenbei_@hust.edu.cn.
Qiong ZhouDepartment of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. zhouqiongtj@hust.edu.cn.

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82170105National Natural Science Foundation of China (National Science Foundation of China) 82370095National Natural Science Foundation of China (National Science Foundation of China) 82400119National Natural Science Foundation of China (National Science Foundation of China) No. 82200113National Natural Science Foundation of China (National Science Foundation of China) No.82300123National Natural Science Foundation of China (National Science Foundation of China) NO.82400119
6 · The paper itself

Abstract

Tumor necrosis factor receptor 2-positive regulatory T (TNFR2

Indexed as

Cancer-Associated FibroblastsHistonesReceptors, Tumor Necrosis Factor, Type IIT-Lymphocytes, RegulatoryAnimalsChemokine CXCL16Disease ProgressionForkhead Box Protein O3HumansMiceReceptors, CXCR6Chemokine CXCL16CXCL16 protein, humanCXCR6 protein, humanForkhead Box Protein O3FOXO3 protein, humanHistonesReceptors, CXCR6Receptors, Tumor Necrosis Factor, Type II

Identifiers

PMID41310104
PMCPMC12686498

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.