Evidence map›Paper›PMID 41310099›Full record

ReviewJournal of cancer survivorship : research and practice2025

The effects of VR/AR/MR-based interventions on symptom management among adult cancer survivors receiving active treatments: a systematic review and meta-analysis.

Kailei Yan, Arsham Alamian, Ardis Hanson, Victoria Loerzel

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of cancer survivorship : research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kailei YanCollege of Nursing, University of Central Florida, 12201 Research Pkwy Suite 300, Orlando, FL, 32826, USA. kailei.yan@ucf.edu.
Arsham AlamianSchool of Nursing and Health Studies, The University of Miami, 5030 Brunson Dr, Coral Gables, FL, 33146, USA.
Ardis HansonShimberg Health Sciences Library, University of South Florida, 12901 Bruce B Downs Blvd, Tampa, FL, 33612, USA.
Victoria LoerzelCollege of Nursing, University of Central Florida, 12201 Research Pkwy Suite 300, Orlando, FL, 32826, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeVirtual Reality (VR)-based interventions emerge as promising tools for symptom management among cancer survivors receiving active treatments. Evidence from previous systematic reviews and meta-analyses is limited by small numbers of studies and lack of sub-group analyses. The purpose of this review was to evaluate the effectiveness of VR/AR/MR interventions on symptom management for cancer survivors receiving active treatments.

methodsFive electronic databases were searched up to March 2025. A meta-analysis was conducted. Sub-group analyses for age, treatment type, cancer type, VR type (immersive or non-immersive), lengths of interventions, scene type, and interaction methods were evaluated.

resultsTwenty-seven unique randomized controlled trials (RCTs) were included. In total, 62 effect sizes for eight symptom outcomes, including fatigue, pain, anxiety, depression, nausea, distress, confusion, and dyspnea, were computed. Meta-analyses showed that the effects of VR interventions were significant on fatigue (n = 12, SMD-0.9494 [- 1.5083, -0.3904]), pain (n = 13, SMD-0.7426 [-1.2694, -0.2158]), and anxiety (n = 16, SMD-1.8063 [-3.0549, -0.5576]). In our sensitivity test, the effect of VR on depression was also significant (n = 8, SMD-0.3682 [-0.5774, -0.1589]). No significant effect was found for outcomes of nausea, distress, confusion, and dyspnea.

conclusionsVR interventions showed efficacy in decreasing fatigue, pain, and anxiety among individuals with cancer receiving active treatment. IMPLICATIONS FOR CANCER SURVIVORS: As the VR interventions demonstrated differential effects across subgroups defined by age, cancer type, treatment type, and their unique VR features, tailored intervention designs are needed to address the specific needs of each patient group.

Indexed as

CancerMeta-analysisSymptomsSystematic reviewVirtual reality

Identifiers

PMID41310099

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.