Evidence map›Paper›PMID 41310021›Full record

ArticleMikrochimica acta2025

Aptamer-driven limited-domain imprinted fluorescent sensor for ultra-sensitive and highly selective detection of Cr(VI).

Xu Yan, Min Yuan, Ye Yang, Bingqian Du, Yanhui Liu, Menghan Fan, Qinyi Wang, Hao Shuang Shen, Hao Zhang, Fei Xu

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Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xu YanSchool of Health Science and Engineering, Shanghai Engineering Research Centre for Food Rapid Detection, University of Shanghai for Science and Technology, Shanghai, 200093, China.
Min YuanSchool of Health Science and Engineering, Shanghai Engineering Research Centre for Food Rapid Detection, University of Shanghai for Science and Technology, Shanghai, 200093, China.
Ye YangSchool of Health Science and Engineering, Shanghai Engineering Research Centre for Food Rapid Detection, University of Shanghai for Science and Technology, Shanghai, 200093, China.
Bingqian DuSchool of Health Science and Engineering, Shanghai Engineering Research Centre for Food Rapid Detection, University of Shanghai for Science and Technology, Shanghai, 200093, China.
Yanhui LiuSchool of Health Science and Engineering, Shanghai Engineering Research Centre for Food Rapid Detection, University of Shanghai for Science and Technology, Shanghai, 200093, China.
Menghan FanSchool of Health Science and Engineering, Shanghai Engineering Research Centre for Food Rapid Detection, University of Shanghai for Science and Technology, Shanghai, 200093, China.
Qinyi WangSchool of Health Science and Engineering, Shanghai Engineering Research Centre for Food Rapid Detection, University of Shanghai for Science and Technology, Shanghai, 200093, China.
Hao Shuang ShenSchool of Health Science and Engineering, Shanghai Engineering Research Centre for Food Rapid Detection, University of Shanghai for Science and Technology, Shanghai, 200093, China.
Hao ZhangSchool of Health Science and Engineering, Shanghai Engineering Research Centre for Food Rapid Detection, University of Shanghai for Science and Technology, Shanghai, 200093, China.
Fei XuSchool of Health Science and Engineering, Shanghai Engineering Research Centre for Food Rapid Detection, University of Shanghai for Science and Technology, Shanghai, 200093, China. xufei8135@126.com.

Funding

Shanghai Agriculture Applied Technology Development Program Grant No. T2024216
6 · The paper itself

Abstract

A limited-domain ion-imprinted fluorescence sensor (LDIFS) was developed by integrating aptamers with ion-imprinted polymers, achieving exceptional sensitivity and selectivity. Aptamers were immobilized on silanized ZnS quantum dots, after which pre-polymerized potassium dichromate and functional monomers were introduced. The polymerization process generated selective imprinted cavities and stabilized the active conformation of aptamer. LDIFS achieves the detection within 15 min by leveraging the inner filter effect. A dual-recognition mechanism, which integrates conformational locking and imprinted cavity memory, synergistically improves the analytical performance of the sensor. The sensor achieves an ultralow detection limit of 0.43 nmol/L, exhibiting 1-3 orders of magnitude higher sensitivity than conventional approaches. A high selectivity factor of 17.9 was attained, ensuring excellent anti-interference capability. The method was successfully applied to the analysis of real squid samples, yielding recoveries ranging from 85.39% to 102.5% with RSD < 3%. This work presents a highly sensitive and selective strategy for chromium ion detection, showcasing its promising applications in environmental monitoring and food safety analysis.

Indexed as

Aptamers, NucleotideBiosensing TechniquesChromiumFluorescent DyesMolecular ImprintingAnimalsLimit of DetectionQuantum DotsSpectrometry, FluorescenceSulfidesZinc CompoundsAptamers, NucleotideChromiumchromium hexavalent ionFluorescent DyesSulfidesZinc Compoundszinc sulfideAptamerCr(VI)Inner filter effectSilanized quantum dots

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.